Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | SPTLC2 | O15270 | 6/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RHOC | P08134 | 3/20 | 0.42 |
| ▸ | RHOA | P61586 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147621 | 1.00 | MGLL (0.49) | MGLLCHRNA7HTR3EHTR3BALOX15 | |
| SCHEMBL4149658 | 0.94 | F2R (0.48) | DRD2DRD4F2RSPTLC2EPHX2 | |
| SCHEMBL4149659 | 0.94 | F2R (0.48) | DRD2DRD4F2RSPTLC2EPHX2 | |
| SCHEMBL4163877 | 0.92 | RHOC (0.49) | MGLLCHRNA7HTR3EHTR3BALOX15 | |
| SCHEMBL4163875 | 0.92 | RHOC (0.49) | MGLLCHRNA7HTR3EHTR3BALOX15 | |
| SCHEMBL4153226 | 0.89 | TACR2 (0.51) | MGLLDRD2DRD4F2RSPTLC2 | |
| SCHEMBL4144599 | 0.88 | SPTLC2 (0.53) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL4144597 | 0.88 | SPTLC2 (0.53) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL4144283 | 0.87 | RHOC (0.43) | MGLLF2RSPTLC2CCR2RHOC | |
| SCHEMBL4144284 | 0.87 | RHOC (0.43) | MGLLF2RSPTLC2CCR2RHOC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470816-B2 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | NTSR2, NTSR1, HNMT | MGLL 3129/4885CHRNA7 539/4885HTR3E 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.