Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 8/20 | 0.48 |
| ▸ | HEXB | P07686 | 8/20 | 0.48 |
| ▸ | DHFR | P00374 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853390 | 0.80 | HEXA (0.37) | HEXAHEXBDHFRMEN1SLC22A1 | |
| SCHEMBL26977987 | 0.77 | HEXA (0.41) | HEXAHEXBDHFRMEN1SLC22A1 | |
| SCHEMBL8259803 | 0.76 | HEXA (0.52) | HEXAHEXBDHFRMEN1SLC22A1 | |
| SCHEMBL12484463 | 0.76 | HEXA (0.48) | HEXAHEXBDHFRMEN1SLC22A1 | |
| SCHEMBL3267542 | 0.74 | HEXA (0.47) | HEXAHEXBDHFRMEN1SLC22A1 | |
| SCHEMBL20503385 | 0.74 | HEXA (0.47) | HEXAHEXBDHFRMEN1SLC22A1 | |
| SCHEMBL6358662 | 0.74 | HEXA (0.47) | HEXAHEXBDHFRMEN1SLC22A1 | |
| SCHEMBL14127794 | 0.74 | HEXA (0.45) | HEXAHEXBDHFRMEN1SLC22A1 | |
| Hydrochloric Acid SCHEMBL18670802 | 0.73 | HEXA (0.46) | HEXAHEXBDHFRMEN1SLC22A1 | |
| SCHEMBL12158710 | 0.73 | LMNA (0.41) | MEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090311318-A1 | SUBSTITUTED (S)-BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090311318-A1 | SUBSTITUTED (S)-BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090311318-A1 | SUBSTITUTED (S)-BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-12-17 | — | — | US | disclosed |
| WO-2009108722-A2 | SUBSTITUTED BENZOXAZINONES | P & H THERAPEUTICS, INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| US-20090215763-A1 | SUBSTITUTED BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090215763-A1 | SUBSTITUTED BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090215763-A1 | SUBSTITUTED BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | GHSR, GIPR, GPR119 | HEXA 3454/4885HEXB 2624/4885DHFR 465/4885 |
| US-20090215763-A1 | SUBSTITUTED BENZOXAZINONES | REN, ACE, AGTR1 | HEXA 2789/4885HEXB 2529/4885DHFR 3515/4885 |
| US-20090311318-A1 | SUBSTITUTED (S)-BENZOXAZINONES | REN, ACE, AGTR1 | HEXA 2850/4885HEXB 2048/4885DHFR 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.