Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083776 | 0.86 | ALDH1A1 (0.54) | CYP11B1CYP11B2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL18398538 | 0.85 | CYP11B2 (0.72) | CYP11B1CYP11B2LRRK2CYP3A4CYP2D6 | |
| SCHEMBL1180940 | 0.83 | NR1H4 (0.51) | CYP11B1CYP11B2AKR1C3ALDH1A1HPGD | |
| SCHEMBL13913075 | 0.81 | CYP11B1 (0.65) | CYP11B1CYP11B2LRRK2ALDH1A1MEN1 | |
| SCHEMBL30107672 | 0.81 | NPC1 (0.67) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL28651978 | 0.81 | NPC1 (0.67) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL10086431 | 0.74 | NPC1 (0.65) | CYP11B1CYP11B2LRRK2CYP3A4CYP2D6 | |
| SCHEMBL1179680 | 0.71 | ALDH1A1 (0.54) | CYP11B1CYP11B2AKR1C3ALDH1A1HPGD | |
| SCHEMBL30107673 | 0.70 | NPC1 (0.62) | CYP11B2ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4716148 | 0.70 | BDKRB1 (0.57) | AKR1C3AKR1C1ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082368-A1 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORPORATION (CA) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082368-A1 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | NGF, BDNF, NTRK2 | CYP11B1 3643/4885CYP11B2 3562/4885LRRK2 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.