Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134996 | 0.91 | GAA (0.40) | CCR1TRPV4SMN1; SMN2GSTO1GAA | |
| SCHEMBL4131367 | 0.88 | CNR2 (0.41) | USP2SMN1; SMN2POLB | |
| SCHEMBL4148569 | 0.88 | GSTO1 (0.43) | CCR1BMP1TRPV4USP2SMN1; SMN2 | |
| SCHEMBL4145501 | 0.79 | PTGES (0.39) | CCR1TRPV4GAAALDH1A1FABP4 | |
| SCHEMBL4134999 | 0.78 | GSTO1 (0.44) | CCR1TRPV4GSTO1GAAALDH1A1 | |
| SCHEMBL4145495 | 0.78 | F13A1 (0.44) | ALDH1A1 | |
| SCHEMBL4148627 | 0.78 | BMP1 (0.37) | CCR1BMP1TRPV4USP2SMN1; SMN2 | |
| SCHEMBL4148621 | 0.78 | BMP1 (0.37) | CCR1BMP1TRPV4USP2SMN1; SMN2 | |
| SCHEMBL4140483 | 0.76 | CCR1 (0.41) | CCR1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL4131370 | 0.76 | CNR2 (0.49) | USP2SMN1; SMN2GSTO1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | TRPV4, TRPC4, TRPV1 | CCR1 766/4885BMP1 2172/4885TRPV4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.