Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152491 | 0.87 | BDKRB1 (0.43) | BDKRB1HTR6F11ACHESMYD3 | |
| SCHEMBL4136765 | 0.82 | BDKRB1 (0.43) | BDKRB1HTR6F11ACHESMYD3 | |
| SCHEMBL4139938 | 0.82 | BDKRB1 (0.37) | BDKRB1F11ACHEOPRD1 | |
| SCHEMBL4142421 | 0.81 | BDKRB1 (0.44) | BDKRB1F11ACHEOPRD1 | |
| SCHEMBL4140540 | 0.78 | HTR6 (0.44) | BDKRB1HTR6ACHEOPRD1 | |
| SCHEMBL4147340 | 0.78 | BDKRB1 (0.43) | BDKRB1F11ACHEMEN1KMT2A | |
| SCHEMBL5956791 | 0.73 | ACHE (0.46) | F11ACHEMEN1KMT2A | |
| SCHEMBL4146216 | 0.72 | BDKRB1 (0.41) | BDKRB1OPRD1 | |
| SCHEMBL4136762 | 0.72 | ACHE (0.39) | BDKRB1F11ACHEOPRD1 | |
| Hydrochloric Acid SCHEMBL355728 | 0.72 | ACHE (0.45) | F11ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048224-A1 | COMPOUNDS AND METHODS OF USE | AMGEN, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| US-7425631-B2 | Compounds and methods of use | AMGEN INC. (US) | 2008-09-16 | — | — | US | disclosed |
| US-20050124654-A1 | Compounds and methods of use | AMGEN INC. | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124654-A1 | Compounds and methods of use | LTC4S, PTGES, LTB4R2 | BDKRB1 51/4885HTR6 1147/4885CSF1R 2403/4885 |
| US-20090048224-A1 | COMPOUNDS AND METHODS OF USE | LTC4S, PTGES, LTB4R2 | BDKRB1 51/4885HTR6 1147/4885CSF1R 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.