Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL8657252 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL41491 | 1.00 | TSHR (0.90) | — | |
| Maleic Acid SCHEMBL29068820 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL6466124 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL41492 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL6466120 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL41494 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL6466117 | 1.00 | TSHR (0.90) | — | |
| Maleic Acid SCHEMBL716254 | 1.00 | — | — | |
| Maleic Acid SCHEMBL716253 | 1.00 | TSHR (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2376 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519449-B1 | METHODS OF PREPARING A CATALYST | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2026-04-08 | — | — | EP | claimed |
| EP-4065236-B1 | METHOD FOR THE DECOLORIZATION OF KERATIN MATERIAL THAT HAS BEEN DYED USING A PIGMENT | HENKEL AG & CO KGAA (DE) | 2025-06-11 | — | — | EP | claimed |
| CN-116514091-B | Preparation method and application of lithium iron phosphate | 河南佰利新能源材料有限公司 | 2025-05-13 | — | — | CN | claimed |
| WO-2025097045-A1 | COLLOIDAL FOOD BASE COMPOSITIONS COMPRISING MYCELIAL BIOMASS | THE FYNDER GROUP, INC (US) | 2025-05-08 | — | — | WO | claimed |
| CN-119866366-A | Dispersing agent and aqueous coating composition | 圣诺普科有限公司 | 2025-04-22 | — | — | CN | claimed |
| CN-119858232-A | Device and method for processing ceramic wet blank by ultrasonic vibration | 中国科学院上海硅酸盐研究所 | 2025-04-22 | — | — | CN | claimed |
| CN-116143129-B | Preparation method and application of peanut-shaped ultra-high-purity silica sol | 万华化学集团股份有限公司 | 2025-04-01 | — | — | CN | claimed |
| CN-119570870-A | Method for synthesizing L-2-aminobutyric acid and L-2-aminobutanamide hydrochloride and application | 浙江永太科技股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| EP-3083040-B1 | HIGH-CONCENTRATION SILVER SOLUTIONS FOR ETHYLENE OXIDE CATALYST PREPARATION | SCIENT DESIGN LLC (US) | 2025-03-05 | — | — | EP | claimed |
| US-12227623-B2 | Water-absorbing hydrogel and method for producing the same | NISSAN CHEMICAL CORPORATION (JP) | 2025-02-18 | — | — | US | claimed |
| EP-0125105-A2 | Immobilization of catalytically active microorganisms in agar gel fibers | PFIZER INC. (US) | 1984-11-14 | — | — | EP | claimed |
| EP-0123903-A2 | Method for producing L-aspartic acid | Tanabe Seiyaku Co., Ltd. (JP) | 1984-11-07 | — | — | EP | claimed |
| US-4456685-A | USING P,P*-DICYANATODIPHENYLMETHANE AND DIMERS AND TRIMERS | W. R. GRACE & CO. (US) | 1984-06-26 | — | — | US | claimed |
| EP-0110422-A2 | Process for producing L-aspartic acid | Tanabe Seiyaku Co., Ltd. (JP) | 1984-06-13 | — | — | EP | claimed |
| US-4436813-A | HAVING L-ASPARTASE ACTIVITY, FROM AMMONIUM FUMARATE | PURIFICATION ENGINEERING, INC. (US) | 1984-03-13 | — | — | US | claimed |
| US-4434228-A | WITH POILYCARBOXYLIC ACID | GENEX CORPORATION (US) | 1984-02-28 | — | — | US | claimed |
| EP-0089165-A2 | Immobilized microbial cells and process for preparing and using same | RHONE-POULENC CHIMIE (FR) | 1983-09-21 | — | — | EP | claimed |
| EP-0032987-A1 | Thermophilic aspartase, processes for producing, culture used, and L-aspartic acid preparation process using the same | KYOWA HAKKO KOGYO CO., LTD (JP) | 1981-08-05 | — | — | EP | claimed |
| US-4232046-A | Liquid starch-urea ruminant feed and method of preparing same | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1980-11-04 | — | — | US | claimed |
| US-3988483-A | Liquid starch-urea ruminant feed and method of producing same | THE KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-10-26 | — | — | US | claimed |