SCHEMBL4149481

SCHEMBL4149481

CN(C(=O)C(O)(c1ccccc1)c1ccccc1)C1C2CCC1CN(Cc1ccccc1)C2

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 1/20 0.46
KCNH2 Q12809 1/20 0.43
ACHE P22303 2/20 0.43
FUCA1 P04066 2/20 0.43
GRIN2B Q13224 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4141323 0.88 ACHE (0.44) KCNH2ACHEFUCA1GRIN2B
SCHEMBL4132636 0.88 KCNH2 (0.43) KCNH2ACHEFUCA1GRIN2B
SCHEMBL7242578 0.83 FUCA1 (0.50) ACHEFUCA1GRIN2B
SCHEMBL4129264 0.81 CHRM2 (0.46) CHRM3
SCHEMBL7248714 0.79 FUCA1 (0.46) ACHEFUCA1GRIN2B
SCHEMBL3527474 0.78 GRIN2B (0.45) ACHEFUCA1GRIN2B
SCHEMBL4141367 0.77 ALDH1A1 (0.40) CHRM3KCNH2
SCHEMBL4136255 0.77 OPRM1 (0.46) ACHEFUCA1GRIN2B
SCHEMBL4127931 0.77 ADRA1A (0.42) CHRM3KCNH2
SCHEMBL4619318 0.76 CHRM3 (0.44) CHRM3ACHEFUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090131410-A1 3-AZABICYCLOOCTANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2009-05-21 US claimed
EP-1934184-A1 3 -AZABICYCLOOCTANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES, LTD. (IN) 2008-06-25 EP claimed
WO-2007039884-A1 3 -AZABICYCLOOCTANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2007-04-12 WO claimed
US-20090131410-A1 3-AZABICYCLOOCTANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2009-05-21 US disclosed
EP-1934184-A1 3 -AZABICYCLOOCTANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES, LTD. (IN) 2008-06-25 EP disclosed
WO-2007039884-A1 3 -AZABICYCLOOCTANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131410-A1 3-AZABICYCLOOCTANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS CHRM3, CHRM2, CHRM5 CHRM3 1/4885KCNH2 797/4885ACHE 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.