Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077683 | 0.82 | SMN1; SMN2 (0.56) | LMNAPPARDMAPTTP53FFAR1 | |
| SCHEMBL12875924 | 0.80 | LMNA (0.54) | LMNAPPARDMAPTTP53FFAR1 | |
| SCHEMBL8989130 | 0.79 | KDM4E (0.54) | LMNAPPARDMAPTTP53FFAR1 | |
| SCHEMBL3372237 | 0.78 | MAPT (0.55) | LMNAMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL28295525 | 0.77 | ALOX5 (0.60) | LMNAMAPTTP53PTGDR2 | |
| SCHEMBL4474091 | 0.76 | LMNA (0.48) | LMNAMAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL95917 | 0.76 | RAB9A (0.56) | LMNAMAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL3371249 | 0.75 | MAPT (0.48) | LMNAPPARDMAPTTP53FFAR1 | |
| SCHEMBL28295520 | 0.75 | CDC7 (0.64) | LMNAMAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL28295517 | 0.75 | CDC7 (0.51) | LMNAMAPTSMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078981-A2 | PPAR-DELTA LIGANDS AND METHODS OF THEIR USE | SRI INTERNATIONAL (US) | 2009-06-25 | — | — | WO | disclosed |
| CN-101007790-A | Oxamic acid derivative, and its preparation method and medicinal uses | BEIJING MOLIKE SCIENCE AND TEC (CN) | 2007-08-01 | — | — | CN | disclosed |