SCHEMBL4151455

SCHEMBL4151455

CC(C)(C)OC(=O)Cn1ccnc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
TBXAS1 P24557 6/20 0.44
EGLN3 Q9H6Z9 1/20 0.43
CYP19A1 P11511 1/20 0.43
BRD4 O60885 1/20 0.42
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PLAA Q9Y263 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HMOX2 P30519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2853083 0.80 ALDH1A1 (0.60) ALDH1A1EGLN3CYP19A1ALPIALPG
SCHEMBL10856981 0.79 ALDH1A1 (0.46) ALDH1A1TBXAS1CYP19A1BRD4
SCHEMBL15883223 0.79 EGLN3 (0.47) ALDH1A1TBXAS1EGLN3
SCHEMBL563845 0.77 ALDH1A1 (0.56) ALDH1A1TBXAS1EGLN3CYP19A1
SCHEMBL6262180 0.77 ALDH1A1 (0.56) ALDH1A1EGLN3CYP19A1ALPIALPG
SCHEMBL4968495 0.77 ALDH1A1 (0.60) ALDH1A1TBXAS1EGLN3CYP19A1ALPI
SCHEMBL4837064 0.76 DTYMK (0.47) ALDH1A1
Hydrochloric Acid SCHEMBL27678497 0.76 ALDH1A1 (0.55) ALDH1A1TBXAS1EGLN3CYP19A1ALPG
SCHEMBL28928213 0.76 ALDH1A1 (0.41) ALDH1A1
Hydrochloric Acid SCHEMBL6893393 0.75 TBXAS1 (0.53) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314701-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2008-01-01 US claimed
CN-117561058-A CDK2 inhibitors and methods of use thereof 塞迪拉治疗股份有限公司 2024-02-13 CN disclosed
US-20230372537-A1 LIPID NANOPARTICLE FORMULATIONS ACUITAS THERAPEUTICS INC (CA) 2023-11-23 US disclosed
US-20230372537-A1 LIPID NANOPARTICLE FORMULATIONS ACUITAS THERAPEUTICS INC (CA) 2023-11-23 US disclosed
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-11712481-B2 Lipid nanoparticle formulations Acuitas Therapeutics, Inc. (CA) 2023-08-01 US disclosed
US-11712481-B2 Lipid nanoparticle formulations Acuitas Therapeutics, Inc. (CA) 2023-08-01 US disclosed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed
WO-2008157050-A1 PROCESSES FOR MANUFACTURING BISPHOSPHONIC ACIDS ALBEMARLE CORPORATION (US) 2008-12-24 WO disclosed
EP-1996599-A2 PROCESS FOR MANUFACTURING BISPHOSPHONIC ACIDS Albermarle Corporation (US) 2008-12-03 EP disclosed
US-7314701-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2008-01-01 US disclosed
WO-2007109542-A2 PROCESS FOR MANUFACTURING BISPHOSPHONIC ACIDS ALBEMARLE CORPORATION (US) 2007-09-27 WO disclosed
WO-2007109542-A2 PROCESS FOR MANUFACTURING BISPHOSPHONIC ACIDS ALBEMARLE CORPORATION (US) 2007-09-27 WO disclosed
US-20050095527-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-05 US disclosed
EP-0773926-A1 DIFLUOROSTATONE ANTIVIRAL AGENTS MERRELL PHARMACEUTICALS INC. (US) 1997-05-21 EP disclosed
WO-1996002499-A1 DIFLUOROSTATONE ANTIVIRAL AGENTS MERRELL PHARMACEUTICALS INC. (US) 1996-02-01 WO disclosed
US-4584008-A FUNGICIDES AND PLANT GROWTH REGULATORS CHEVRON RESEARCH COMPANY (US) 1986-04-22 US disclosed
EP-0102163-A1 Triazole derivatives and compositions containing the same CHEVRON RESEARCH COMPANY (US) 1984-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11712481-B2 Lipid nanoparticle formulations LIPA, PLIN3, PLIN1 ALDH1A1 1911/4885TBXAS1 1317/4885EGLN3 225/4885
US-20230372537-A1 LIPID NANOPARTICLE FORMULATIONS LIPA, PLIN3, PLIN1 ALDH1A1 1911/4885TBXAS1 1317/4885EGLN3 225/4885
US-11771715-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB ALDH1A1 4484/4885TBXAS1 2858/4885EGLN3 2566/4885
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB ALDH1A1 4484/4885TBXAS1 2858/4885EGLN3 2566/4885
US-11766449-B2 Circular RNA compositions and methods RTCB, RNGTT, HNRNPAB ALDH1A1 4532/4885TBXAS1 2889/4885EGLN3 3028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.