Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151850 | 0.83 | FABP3 (0.48) | ADORA3ADORA2AADORA1TP53HPGD | |
| SCHEMBL8037289 | 0.80 | GABRA2 (0.44) | ADORA3ADORA2AADORA1TP53HPGD | |
| SCHEMBL4011569 | 0.77 | PDE4B (0.36) | ADORA3ADORA1TP53MAPTTSHR | |
| SCHEMBL4007862 | 0.76 | NAMPT (0.38) | ADORA3TP53BCHEACHELIPE | |
| SCHEMBL4011472 | 0.76 | MAPT (0.39) | ADORA3HPGDBCHEACHELIPE | |
| SCHEMBL4005144 | 0.75 | PPARA (0.39) | ADORA3TP53HSD17B10MAPTNPC1 | |
| SCHEMBL4010068 | 0.72 | PPARG (0.40) | ADORA3BCHEACHELIPEHSD17B10 | |
| SCHEMBL4007708 | 0.70 | CYP1A2 (0.40) | ADORA3TP53MAPTRAB9APOLB | |
| SCHEMBL12929476 | 0.70 | MEN1 (0.59) | ADORA3ADORA2AADORA1TP53HPGD | |
| SCHEMBL12929363 | 0.68 | MEN1 (0.60) | TP53HPGDHSD17B10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |