Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 4/20 | 0.48 |
| ▸ | FABP4 | P15090 | 4/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037289 | 0.87 | GABRA2 (0.44) | TP53HPGDADORA3ADORA2AADORA1 | |
| SCHEMBL4151852 | 0.83 | ADORA3 (0.44) | FABP3FABP4FABP5TP53HPGD | |
| SCHEMBL5961069 | 0.79 | FABP3 (0.49) | FABP3FABP4FABP5TP53ADORA3 | |
| SCHEMBL4011568 | 0.75 | FABP4 (0.42) | FABP3FABP4FABP5TP53ADORA3 | |
| SCHEMBL4011470 | 0.74 | FABP3 (0.45) | FABP3FABP4FABP5HPGDADORA3 | |
| SCHEMBL4007857 | 0.74 | FABP3 (0.45) | FABP3FABP4FABP5TP53HPGD | |
| SCHEMBL8043493 | 0.74 | PLA2G1B (0.45) | FABP3FABP4FABP5ADORA3ADORA2A | |
| SCHEMBL8030010 | 0.74 | RXRA (0.47) | FABP3FABP4FABP5TP53HPGD | |
| SCHEMBL4005140 | 0.73 | FABP3 (0.44) | FABP3FABP4FABP5TP53HPGD | |
| SCHEMBL8025238 | 0.73 | RXRA (0.48) | FABP3FABP4FABP5TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |