SCHEMBL4153679

SCHEMBL4153679

NC(Cn1cccn1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.51
TSHR P16473 1/20 0.49
GRIA1 P42261 2/20 0.41
GRIA2 P42262 2/20 0.41
GRIA4 P48058 2/20 0.41
GRIK5 Q16478 1/20 0.41
HDAC1 Q13547 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HTT P42858 1/20 0.40
TYR P14679 1/20 0.38
DOHH Q9BU89 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 1/20 0.37
NLRP3 Q96P20 1/20 0.36
ARG1 P05089 1/20 0.36
KMO O15229 1/20 0.36
ALPI P09923 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9462503 1.00 FDPS (0.51) FDPSTSHRGRIA1GRIA2GRIA4
SCHEMBL503649 1.00 FDPS (0.51) FDPSTSHRGRIA1GRIA2GRIA4
Hydrochloric Acid SCHEMBL7471557 0.98 FDPS (0.50) FDPSTSHRGRIA1GRIA2GRIA4
SCHEMBL10222182 0.84 FDPS (0.50) FDPSTSHRHDAC1HDAC6HTT
SCHEMBL5322003 0.82 ARG1 (0.44) FDPSTSHRGRIA1GRIA2GRIA4
SCHEMBL15208660 0.82 ARG1 (0.44) FDPSTSHRGRIA1GRIA2GRIA4
SCHEMBL10206691 0.81 FDPS (0.47) FDPSTSHRHDAC1HDAC6HTT
SCHEMBL15209057 0.80 ARG1 (0.52) FDPSTSHRALDH1A1TDP1CYP1A2
SCHEMBL15209056 0.80 ARG1 (0.52) FDPSTSHRALDH1A1TDP1CYP1A2
SCHEMBL8781449 0.80 FDPS (0.46) FDPSTSHRHDAC1HDAC6HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115015460-B Method for identifying cordyceps sinensis producing area by using wide-range targeted metabonomics technology 中国检验检疫科学研究院 2024-05-03 CN claimed
CN-115015460-A Method for identifying producing area of cordyceps sinensis by using extensive targeted metabonomics technology 中国检验检疫科学研究院 2022-09-06 CN claimed
EP-3335720-A1 C-DI-GMP BINDING PEPTIDES Universität Basel (CH) 2018-06-20 EP claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
WO-2024108198-A2 METHODS OF TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS, INC. (US) 2024-05-23 WO disclosed
CN-115015460-B Method for identifying cordyceps sinensis producing area by using wide-range targeted metabonomics technology 中国检验检疫科学研究院 2024-05-03 CN disclosed
WO-2024015880-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS, INC. (US) 2024-01-18 WO disclosed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
CN-115093463-A Beta-hairpin peptidomimetics 波利弗尔股份公司 2022-09-23 CN disclosed
CN-115015460-A Method for identifying producing area of cordyceps sinensis by using extensive targeted metabonomics technology 中国检验检疫科学研究院 2022-09-06 CN disclosed
US-20220160818-A1 PHARMACEUTICAL COMPOSITIONS RHYTHM PHARMACEUTICALS, INC. 2022-05-26 US disclosed
CN-114269367-A Therapeutic peptides 科巴公司 2022-04-01 CN disclosed
US-5646167-A ADMINISTERED AS METALLOPROTEINASE INHIBITOR, ANTITUMOR OR ANTICARCINOGENIC AGENT CIBA-GEIGY CORPORATION (US) 1997-07-08 US disclosed
US-5552419-A METALLOPROTEINASE INHIBITORS CIBA-GEIGY CORPORATION (US) 1996-09-03 US disclosed
WO-1996012499-A1 AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-05-02 WO disclosed
US-5506242-A METALLOELASTASE INHIBITOR; TREATS EMPHYSEMA CIBA-GEIGY CORPORATION (US) 1996-04-09 US disclosed
US-5455258-A Useful as inhibitors of matrix-degrading metalloproteinase enzymes such as stromelysin and/or collegenase CIBA-GEIGY CORPORATION (US) 1995-10-03 US disclosed
EP-0606046-A1 Arylsulfonamido-substituted hydroxamic acids CIBA-GEIGY AG (CH) 1994-07-13 EP disclosed
EP-0350163-A2 Renin inhibitory peptides BEECHAM GROUP PLC (GB) 1990-01-10 EP disclosed
US-4328134-A Anorexigenic peptides ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND, THE, A CORP. OF LA 1982-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160818-A1 PHARMACEUTICAL COMPOSITIONS PCTP, SLC27A1, CETP FDPS 1109/4885TSHR 1147/4885GRIA1 1041/4885
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP FDPS 2740/4885TSHR 182/4885GRIA1 2608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.