Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188369 | 0.98 | CYP2A6 (0.30) | — | |
| SCHEMBL29750724 | 0.98 | CYP2A6 (0.30) | — | |
| SCHEMBL17668116 | 0.92 | HTR2A (0.37) | — | |
| SCHEMBL6271251 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL56849 | 0.86 | CYP2A6 (0.32) | — | |
| SCHEMBL29206144 | 0.84 | — | — | |
| SCHEMBL23488 | 0.84 | HTR2A (0.40) | — | |
| SCHEMBL29356973 | 0.84 | HTR2A (0.40) | — | |
| SCHEMBL5058499 | 0.82 | HTR2A (0.40) | — | |
| SCHEMBL17668115 | 0.82 | HTR2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133551-B | Pyrimidine polyether and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-114133551-A | Pyrimidyl polyether and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-03-04 | — | — | CN | claimed |
| EP-2951279-B1 | METHOD AND CULTURE DEVICE FOR DETECTING YEASTS AND MOLDS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-12-09 | — | — | EP | disclosed |
| US-10640743-B2 | Method and culture device for detecting yeasts and molds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-05-05 | — | — | US | disclosed |
| EP-3553163-A1 | ARTICLE AND METHOD FOR DETECTING AEROBIC BACTERIA | 3M Innovative Properties Company (US) | 2019-10-16 | — | — | EP | disclosed |
| EP-3114209-B1 | ARTICLE AND METHOD FOR DETECTING AEROBIC BACTERIA | 3M INNOVATIVE PROPERTIES CO (US) | 2019-06-12 | — | — | EP | disclosed |
| US-20180148675-A1 | METHOD AND CULTURE DEVICE FOR DETECTING YEASTS AND MOLDS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-05-31 | — | — | US | disclosed |
| US-9879214-B2 | Method and culture device for detecting yeasts and molds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-01-30 | — | — | US | disclosed |
| US-20170073629-A1 | ARTICLE AND METHOD FOR DETECTING AEROBIC BACTERIA | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-03-16 | — | — | US | disclosed |
| US-20160032231-A1 | METHOD AND CULTURE DEVICE FOR DETECTING YEASTS AND MOLDS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-02-04 | — | — | US | disclosed |
| US-8921067-B2 | Method and culture device for detecting yeasts and molds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140220610-A1 | METHOD AND CULTURE DEVICE FOR DETECTING YEASTS AND MOLDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140120098-A1 | FIBCD1 FOR THE PREVENTION AND TREATMENT OF DISEASES | MucoVax, Inc. (BS) | 2014-05-01 | — | — | US | disclosed |
| US-20120020958-A1 | FIBCD1 FOR THE PREVENTION AND TREATMENT OF DISEASES | Dansk Universitet (DK) | 2012-01-26 | — | — | US | disclosed |
| EP-2379102-A1 | FIBCD1 FOR THE PREVENTION AND TREATMENT OF DISEASES | Syddansk Universitet (DK) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010075891-A1 | FIBCD1 FOR THE PREVENTION AND TREATMENT OF DISEASES | SYDDANSK UNIVERSITET (DK) | 2010-07-08 | — | — | WO | disclosed |
| EP-0870054-B1 | METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS | BIOCONTROL SYSTEMS INC (US) | 2008-07-30 | — | — | EP | disclosed |
| US-6387650-B1 | INNOCULATING AND INCUBATING TEST SAMPLE ON GROWTH MEDIUM HAVING ENZYME SUBSTRATES FOR PHOSPHATASE, GLYCOSIDASE, AND PEPTIDASE, THEN DETECTING OR MEASURING SIGNAL PRODUCED BY THE HYDROLYSIS OF THE SUBSTRATES | BIOCONTROL SYSTEMS, INC. | 2002-05-14 | — | — | US | disclosed |
| EP-0870054-A1 | METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS | IDEXX LABORATORIES, INC. (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996040980-A1 | METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS | IDEXX LABORATORIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |