Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915368 | 0.83 | L3MBTL1 (0.59) | MAPTPKMPOLBUSP2MEN1 | |
| SCHEMBL4790629 | 0.83 | ALDH1A1 (0.57) | PKMPOLBUSP2KDM4EMEN1 | |
| SCHEMBL3236916 | 0.82 | MAPT (0.80) | MAPTPKMPOLBUSP2KDM4E | |
| SCHEMBL423283 | 0.82 | MAPT (0.74) | MAPTPKMPOLBUSP2MEN1 | |
| SCHEMBL4554939 | 0.80 | USP2 (0.80) | MAPTPKMPOLBUSP2KDM4E | |
| SCHEMBL7096080 | 0.80 | USP2 (0.80) | MAPTPKMPOLBUSP2KDM4E | |
| SCHEMBL23362155 | 0.80 | LMNA (0.59) | USP2LMNAALDH1A1 | |
| SCHEMBL16964845 | 0.79 | PKM (0.68) | MAPTPKMPOLBUSP2KDM4E | |
| SCHEMBL1711115 | 0.78 | PKM (0.85) | MAPTPKMPOLBUSP2KDM4E | |
| SCHEMBL4002592 | 0.75 | PKM (0.64) | PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |