Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779566 | 1.00 | HAO1 (0.61) | HAO1KMT2AMAPTMEN1SOAT1 | |
| SCHEMBL7145261 | 1.00 | HAO1 (0.61) | HAO1KMT2AMAPTMEN1SOAT1 | |
| SCHEMBL21654254 | 1.00 | HAO1 (0.61) | HAO1KMT2AMAPTMEN1SOAT1 | |
| SCHEMBL7913988 | 1.00 | HAO1 (0.61) | HAO1KMT2AMAPTMEN1SOAT1 | |
| SCHEMBL2942506 | 1.00 | HAO1 (0.61) | HAO1KMT2AMAPTMEN1SOAT1 | |
| SCHEMBL2419176 | 1.00 | HAO1 (0.61) | HAO1KMT2AMAPTMEN1SOAT1 | |
| SCHEMBL1515939 | 1.00 | HAO1 (0.61) | HAO1KMT2AMAPTMEN1SOAT1 | |
| SCHEMBL28755152 | 0.98 | HAO1 (0.59) | HAO1KMT2AMAPTMEN1SOAT1 | |
| Hydrochloric Acid SCHEMBL27516387 | 0.98 | HAO1 (0.59) | HAO1KMT2AMAPTMEN1SOAT1 | |
| SCHEMBL7150300 | 0.98 | HAO1 (0.57) | HAO1KMT2AMAPTMEN1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411397-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ECOLE NORMALE SUPERIEURE (FR) | 2022-12-29 | — | — | US | disclosed |
| CN-115209891-A | Analogs of N-acyl-homoserine lactones and pharmaceutical compositions containing the same | 索邦大学 | 2022-10-18 | — | — | CN | disclosed |
| WO-2021078952-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SORBONNE UNIVERSITE (FR) | 2021-04-29 | — | — | WO | disclosed |
| US-10988571-B2 | Quorum sensing based polymer for stimulation of biofilms and related phenotypes, and synthesis process thereof | FIB-SOL Life Technologies Private Limited (IN) | 2021-04-27 | — | — | US | disclosed |
| US-20200031989-A1 | QUORUM SENSING BASED POLYMER FOR STIMULATION OF BIOFILMS AND RELATED PHENOTYPES, AND SYNTHESIS PROCESS THEREOF | FIB-SOL Life Technologies Private Limited (IN) | 2020-01-30 | — | — | US | disclosed |
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
| WO-2009077844-A2 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | QUONOVA LLC (US) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10988571-B2 | Quorum sensing based polymer for stimulation of biofilms and related phenotypes, and synthesis process thereof | PGLS, COASY, FDPS | HAO1 618/4885KMT2A 4081/4885MAPT 4738/4885 |
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | PGLS, TFPI, Q6ZSR9 | HAO1 2939/4885KMT2A 3636/4885MAPT 3184/4885 |
| US-20200031989-A1 | QUORUM SENSING BASED POLYMER FOR STIMULATION OF BIOFILMS AND RELATED PHENOTYPES, AND SYNTHESIS PROCESS THEREOF | PGLS, COASY, FDPS | HAO1 618/4885KMT2A 4081/4885MAPT 4738/4885 |
| US-20220411397-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AHCYL1, LTC4S, AHCY | HAO1 2028/4885KMT2A 3751/4885MAPT 3125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.