Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS9 | O00182 | 5/20 | 0.47 |
| ▸ | LGALS1 | P09382 | 5/20 | 0.47 |
| ▸ | LGALS3 | P17931 | 5/20 | 0.47 |
| ▸ | LGALS7; LGALS7B | P47929 | 4/20 | 0.47 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048538 | 0.85 | LGALS9 (0.46) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL13192007 | 0.83 | LGALS3 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL4331137 | 0.82 | LGALS3 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL4331140 | 0.82 | LGALS3 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL13612938 | 0.82 | LGALS3 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL4331132 | 0.82 | LGALS3 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL28121996 | 0.81 | LGALS9 (0.50) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL16647467 | 0.81 | LGALS9 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL15241392 | 0.81 | LGALS9 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1 | |
| SCHEMBL5202139 | 0.80 | ALDH1A1 (0.46) | POLBGAAALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221811-A1 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2009-09-03 | — | — | US | disclosed |
| WO-2008129530-A1 | GEMCITABINE PRODUCTION PROCESS | CHEMAGIS LTD. (IL) | 2008-10-30 | — | — | WO | disclosed |
| US-20080262215-A1 | GEMCITABINE PRODUCTION PROCESS | CHEMAGIS LTD. (IL) | 2008-10-23 | — | — | US | disclosed |
| EP-1931693-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2008-06-18 | — | — | EP | disclosed |
| US-20070249823-A1 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-10-25 | — | — | US | disclosed |
| WO-2007092705-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-08-16 | — | — | WO | disclosed |
| US-20070191598-A1 | Process for Preparing Gemcitabine and Associated Intermediates | CHEMAGIS LTD. (IL) | 2007-08-16 | — | — | US | disclosed |
| WO-2007070804-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-06-21 | — | — | WO | disclosed |
| WO-2007027564-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249823-A1 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | DPYD, PARP1, PARP2 | LGALS9 1046/4885LGALS1 1515/4885LGALS3 904/4885 |
| US-20080262215-A1 | GEMCITABINE PRODUCTION PROCESS | SAMHD1, DCK, DCTD | LGALS9 956/4885LGALS1 1750/4885LGALS3 1391/4885 |
| US-20070191598-A1 | Process for Preparing Gemcitabine and Associated Intermediates | DCTD, DPYD, THPO | LGALS9 1692/4885LGALS1 2872/4885LGALS3 1715/4885 |
| US-20090221811-A1 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | THPO, DPYD, DCTD | LGALS9 1701/4885LGALS1 2661/4885LGALS3 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.