Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145646 | 0.81 | L3MBTL1 (0.33) | L3MBTL1GLAHTTHSD17B10CRHR1 | |
| SCHEMBL12240479 | 0.78 | CCR1 (0.37) | HSD17B10PDK2HPGD | |
| SCHEMBL30400470 | 0.78 | PIK3CD (0.51) | L3MBTL1GLAHTTHSD17B10PIK3CD | |
| SCHEMBL2366596 | 0.78 | PIK3CD (0.51) | L3MBTL1GLAHTTHSD17B10PIK3CD | |
| SCHEMBL16404975 | 0.77 | AGBL2 (0.43) | HTTHPGD | |
| SCHEMBL10387514 | 0.77 | L3MBTL1 (0.42) | L3MBTL1GLAHTTHSD17B10PIK3CD | |
| SCHEMBL16274509 | 0.77 | AGBL2 (0.38) | L3MBTL1HSD17B10CRHR1HPGDIDO1 | |
| SCHEMBL14019047 | 0.76 | L3MBTL1 (0.42) | L3MBTL1GLAHTTHSD17B10PIK3CD | |
| SCHEMBL12946093 | 0.75 | HPGD (0.32) | HSD17B10HPGDIDO1 | |
| SCHEMBL19349268 | 0.75 | GAA (0.42) | GLAHSD17B10PIK3CDHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118286-A1 | Heterobicyclic Acrylamides | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | US | claimed |
| CN-101171255-A | Heterobicyclic acrylamides | BAYER CROPSCIENCE AG (DE) | 2008-04-30 | — | — | CN | claimed |
| EP-1858899-A1 | HETEROBICYCLIC ACRYLAMIDES | Bayer CropScience AG (DE) | 2007-11-28 | — | — | EP | claimed |
| WO-2006094666-A1 | HETEROBICYCLIC ACRYLAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-09-14 | — | — | WO | claimed |
| US-10870638-B2 | Pyridazinone compound or its salt, and herbicide containing it | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2020-12-22 | — | — | US | disclosed |
| US-20200172517-A1 | PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |
| US-20160235748-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES, INC. | 2016-08-18 | — | — | US | disclosed |
| WO-2016115463-A1 | INHIBITORS OF PHOSPHOGLYCERATE DEHYDROGENASE (PHGDH) AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-07-21 | — | — | WO | disclosed |
| WO-2013096681-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| US-20090118286-A1 | Heterobicyclic Acrylamides | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20080214552-A1 | Substituted Pyridazinecarboxamides and Derivatives Thereof | BAYER CROPSCIENCE AG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20080214552-A1 | Substituted Pyridazinecarboxamides and Derivatives Thereof | BAYER CROPSCIENCE AG (DE) | 2008-09-04 | — | — | US | disclosed |
| CN-101171255-A | Heterobicyclic acrylamides | BAYER CROPSCIENCE AG (DE) | 2008-04-30 | — | — | CN | disclosed |
| EP-1858899-A1 | HETEROBICYCLIC ACRYLAMIDES | Bayer CropScience AG (DE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006094666-A1 | HETEROBICYCLIC ACRYLAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214552-A1 | Substituted Pyridazinecarboxamides and Derivatives Thereof | PFAS, CYP4Z1, CYP4F12 | L3MBTL1 3857/4885GLA 2816/4885HTT 3606/4885 |
| US-10870638-B2 | Pyridazinone compound or its salt, and herbicide containing it | H1-0, H1-4, H1-3 | L3MBTL1 1491/4885GLA 3134/4885HTT 1349/4885 |
| US-20090118286-A1 | Heterobicyclic Acrylamides | CCNB1, C3AR1, CCNA2 | L3MBTL1 1095/4885GLA 4258/4885HTT 157/4885 |
| US-20200172517-A1 | PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT | H1-0, H1-4, H1-3 | L3MBTL1 1491/4885GLA 3134/4885HTT 1349/4885 |
| US-20160235748-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | TYMP, ZC3HAV1, TYMS | L3MBTL1 2667/4885GLA 3000/4885HTT 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.