Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | PTGIR | P43119 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168860 | 0.88 | ADRA2C (0.67) | ADRA2CPTGIRALDH1A1MEN1KMT2A | |
| SCHEMBL10794042 | 0.83 | ALDH1A1 (0.66) | ADRA2CPTGIRPKMALDH1A1MEN1 | |
| SCHEMBL11733716 | 0.83 | ALDH1A1 (0.50) | ADRA2CPTGIRPKMALDH1A1MEN1 | |
| SCHEMBL4155161 | 0.83 | RAB9A (0.56) | ADRA2CALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1928093 | 0.81 | PKM (0.54) | ADRA2CPTGIRPKMALDH1A1MEN1 | |
| SCHEMBL4161794 | 0.78 | ADRA2C (0.73) | ADRA2CPTGIRALDH1A1MEN1KMT2A | |
| SCHEMBL20218944 | 0.77 | LTB4R2 (0.62) | ADRA2CPKMMEN1KMT2ANPC1 | |
| SCHEMBL4163289 | 0.77 | TSHR (0.52) | ADRA2CALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9809224 | 0.77 | HPGD (0.66) | PKMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9001626 | 0.76 | ADRA2C (0.65) | ADRA2CALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | ADRA2C 292/4885PTGIR 845/4885PKM 1638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.