SCHEMBL4156640

SCHEMBL4156640

C[SiH2]c1ccccc1[SiH2]C

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ACHE P22303 2/20 0.35
ALOX12 P18054 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2A6 P11509 1/20 0.31
CYP1A2 P05177 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1054362 0.81
SCHEMBL29776859 0.81
SCHEMBL6859177 0.78
SCHEMBL2316971 0.78
SCHEMBL29568659 0.78
SCHEMBL31216271 0.74 GABRA1 (0.42) MAPTMGLL
SCHEMBL4582431 0.74 ALDH1A1 (0.48) TSHRHPGDHSD17B10CYP2A6CYP1A2
SCHEMBL31216267 0.74 GABRA1 (0.46) TSHRLMNAMAPTHPGDMGLL
SCHEMBL21201761 0.74
SCHEMBL355019 0.73 ALDH1A1 (0.44) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6924545-B2 Low-dielectric-constant interlayer insulating film composed of borazine-silicon-based polymer and semiconductor device NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) 2005-08-02 US claimed
US-20020142533-A1 Low-dielectric-constant interlayer insulating film composed of borazine-silicon-based polymer and semiconductor device MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-10-03 US claimed
US-8362199-B2 Borazine-based resin, process for its production, borazine-based resin composition, insulating film and method for its formation HITACHI CHEMICAL CO., LTD. (JP) 2013-01-29 US disclosed
US-20110313122-A1 BORAZINE-BASED RESIN, PROCESS FOR ITS PRODUCTION, BORAZINE-BASED RESIN COMPOSITION, INSULATING FILM AND METHOD FOR ITS FORMATION MATSUTANI HIROSHI (JP) 2011-12-22 US disclosed
US-7625642-B2 Borazine-based resin, and method for production thereof, borazine based resin composition, insulating coating and method for formation thereof, and electronic parts having the insulating coating HITACHI CHEMICAL CO., LTD (JP) 2009-12-01 US disclosed
US-20090240017-A1 Borazine-based resin, process for its production, borazine-based resin composition, insulating film and method for its formation HITACHI CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
US-7427443-B2 Low dielectric constant insulating material and semiconductor device using the material NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-23 US disclosed
US-20060110610-A1 Borazine-based resin, and method for production thereof, borazine based resin composition, insulating coating and method for formation thereof, and electronic parts having the insulating coating NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-05-25 US disclosed
US-20060097393-A1 Low dielectric constant insulating material and semiconductor device using the material NATIONAL INST. OF ADV. INDUST. SCIENCE AND TECH. (JP) 2006-05-11 US disclosed
US-6924545-B2 Low-dielectric-constant interlayer insulating film composed of borazine-silicon-based polymer and semiconductor device NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) 2005-08-02 US disclosed
US-20020142533-A1 Low-dielectric-constant interlayer insulating film composed of borazine-silicon-based polymer and semiconductor device MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313122-A1 BORAZINE-BASED RESIN, PROCESS FOR ITS PRODUCTION, BORAZINE-BASED RESIN COMPOSITION, INSULATING FILM AND METHOD FOR ITS FORMATION GRIK5, GJA1, SLC9A5 TSHR 3288/4885ACHE 1011/4885ALOX12 1115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.