Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155338 | 0.85 | MEN1 (0.37) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL16707489 | 0.83 | ALDH1A1 (0.37) | ALDH1A1PKMHPGDHTTL3MBTL1 | |
| SCHEMBL4145114 | 0.82 | MEN1 (0.32) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL3626292 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2AHSD17B10ALDH1A1PKM | |
| SCHEMBL16707479 | 0.75 | PDE2A (0.33) | ALDH1A1 | |
| SCHEMBL13105763 | 0.74 | TAS2R14 (0.39) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL8095674 | 0.73 | IDO1 (0.39) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL4150005 | 0.73 | — | — | |
| SCHEMBL9367675 | 0.72 | TRPA1 (0.37) | MEN1ALOX15KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3626269 | 0.72 | ALDH1A1 (0.39) | TSHRMAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176786-A1 | Benzoylurea Compounds and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176786-A1 | Benzoylurea Compounds and Use Thereof | BTK, BRIX1, NFXL1 | MEN1 1863/4885ALOX15 3375/4885TSHR 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.