Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4142290 | 0.88 | KDM4E (0.34) | — | |
| SCHEMBL4157937 | 0.84 | ESR1 (0.34) | LMNASMN1; SMN2MEN1ALOX15TSHR | |
| SCHEMBL4148250 | 0.84 | — | — | |
| SCHEMBL3625294 | 0.83 | KDM4E (0.39) | LMNASMN1; SMN2MEN1ALOX15TSHR | |
| SCHEMBL4150588 | 0.83 | PTGS2 (0.31) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL10505112 | 0.81 | HDAC1 (0.47) | SMN1; SMN2MEN1MAPK1KMT2A | |
| SCHEMBL4158093 | 0.80 | MEN1 (0.36) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL4151004 | 0.77 | KMT2A (0.37) | LMNAMEN1ALOX15TSHRMAPK1 | |
| SCHEMBL4145556 | 0.76 | POLB (0.36) | LMNASMN1; SMN2MEN1MAPK1KMT2A | |
| SCHEMBL4145587 | 0.75 | ALDH1A1 (0.41) | LMNASMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176786-A1 | Benzoylurea Compounds and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-09 | — | — | US | disclosed |
| US-20090176786-A1 | Benzoylurea Compounds and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176786-A1 | Benzoylurea Compounds and Use Thereof | BTK, BRIX1, NFXL1 | LMNA 2141/4885SMN1; SMN2 2011/4885MEN1 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.