Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.50 |
| ▸ | FEN1 | P39748 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704655 | 0.85 | PSIP1 (0.50) | PTGS2ALOX5APFEN1SMN1; SMN2PSIP1 | |
| SCHEMBL2449150 | 0.83 | PTGS2 (0.50) | PTGS2ALOX5APFEN1PTGS1SMN1; SMN2 | |
| SCHEMBL6297018 | 0.82 | ALOX5AP (0.50) | PTGS2ALOX5APFEN1PSIP1 | |
| SCHEMBL6904881 | 0.81 | PTGS2 (0.68) | PTGS2ALOX5APFEN1PTGS1HSD11B1 | |
| SCHEMBL9797523 | 0.81 | HSD11B1 (0.57) | PTGS2ALOX5APFEN1PTGS1HSD11B1 | |
| SCHEMBL2008147 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1HSD11B1SLC6A4SLC6A3 | |
| SCHEMBL778751 | 0.78 | PTGS2 (0.53) | PTGS2ALOX5APFEN1PTGS1HSD11B1 | |
| SCHEMBL2568289 | 0.78 | PTGS2 (0.68) | PTGS2ALOX5APFEN1PTGS1HSD11B1 | |
| SCHEMBL6236983 | 0.78 | ALOX5AP (0.62) | ALOX5APFEN1 | |
| SCHEMBL15366568 | 0.77 | FEN1 (0.54) | PTGS2ALOX5APFEN1PTGS1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227603-A1 | LEUKOTRIENE B4 INHIBITORS | DOMINIQUE ROMYR | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227603-A1 | LEUKOTRIENE B4 INHIBITORS | LTB4R2, LTB4R, LTC4S | PTGS2 40/4885ALOX5AP 17/4885FEN1 4636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.