SCHEMBL4159366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1146161	0.85	HSD11B1 (0.59)	HSD11B1HTR6LMNATSHRABCC9
	SCHEMBL28541788	0.83	HSD11B1 (0.61)	HSD11B1LMNAABCC9ABCC8KCNJ11
	SCHEMBL3157029	0.83	HSD11B1 (0.57)	HSD11B1HTR6LMNAABCC9ABCC8
	SCHEMBL28539914	0.83	HSD11B1 (0.61)	HSD11B1LMNACYP3A4CYP2C9TSHR
	SCHEMBL9713772	0.83	HTR6 (0.50)	HSD11B1HTR6LMNACYP3A4CYP2C9
	SCHEMBL30468568	0.81	ALDH1A1 (0.62)	HSD11B1LMNATSHRABCC9ABCC8
	SCHEMBL3790370	0.81	HTR6 (0.69)	HTR6LMNACYP3A4CYP2C9TSHR
	SCHEMBL8514629	0.81	ALDH1A1 (0.62)	HSD11B1LMNATSHRABCC9ABCC8
	SCHEMBL10692275	0.80	ALDH1A1 (0.57)	HSD11B1HTR6LMNACYP3A4CYP2C9
	SCHEMBL5284219	0.79	HSD11B1 (0.53)	HSD11B1HTR6LMNACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.