Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509486 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL415952 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL19996007 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL19996008 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL3694690 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL6509484 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL10198953 | 0.98 | ALDH1A1 (0.58) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL9607106 | 0.95 | ALDH1A1 (0.56) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL8611206 | 0.92 | TSHR (0.56) | ALDH1A1LMNAEPHX2TSHRCNR2 | |
| SCHEMBL8838716 | 0.92 | TSHR (0.56) | ALDH1A1LMNAEPHX2TSHRCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515885-B1 | PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES | UMICORE AG & CO KG (DE) | 2023-12-13 | — | — | EP | disclosed |
| CN-109982995-B | Preparation of amino acids and amino acid derivatives | 优美科股份公司及两合公司 | 2022-09-30 | — | — | CN | disclosed |
| US-10774035-B2 | Preparation of amino acids and amino acid derivatives | UMICORE AG & CO. KG (DE) | 2020-09-15 | — | — | US | disclosed |
| US-20190276388-A1 | PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES | UMICORE AG & CO KG (DE) | 2019-09-12 | — | — | US | disclosed |
| US-10087137-B2 | Cross metathesis approach to C11-C13 fatty-chain amino esters from oleic acid derivatives | THE UNIVERSITY OF TOLEDO (US) | 2018-10-02 | — | — | US | disclosed |
| EP-3281931-A1 | METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS | Elevance Renewable Sciences, Inc. (US) | 2018-02-14 | — | — | EP | disclosed |
| US-20170204051-A1 | Cross Metathesis Approach to C11-C13 Fatty-Chain Amino Esters From Oleic Acid Derivatives | THE UNIVERSITY OF TOLEDO (US) | 2017-07-20 | — | — | US | disclosed |
| US-8455698-B2 | Hydroxy- and aldehyde functional compounds | EVONIK DEGUSSA GMBH (DE) | 2013-06-04 | — | — | US | disclosed |
| US-8394996-B2 | Method for producing aldehyde functional compounds | EVONIK DEGUSSA GMBH (DE) | 2013-03-12 | — | — | US | disclosed |
| US-20120022276-A1 | METHOD FOR PRODUCING ALDEHYDE FUNCTIONAL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20110198535-A1 | HYDROXY- AND ALDEHYDE FUNCTIONAL COMPOUNDS | EVONIC DEGUSSA GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022276-A1 | METHOD FOR PRODUCING ALDEHYDE FUNCTIONAL COMPOUNDS | FASN, ALDH2, ALOX12 | ALDH1A1 11/4885LMNA 1519/4885EPHX2 121/4885 |
| US-20190276388-A1 | PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES | AADAT, BCAT1, BCAT2 | ALDH1A1 911/4885LMNA 3915/4885EPHX2 3117/4885 |
| US-10774035-B2 | Preparation of amino acids and amino acid derivatives | AADAT, BCAT1, BCAT2 | ALDH1A1 911/4885LMNA 3915/4885EPHX2 3117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.