Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153368 | 0.92 | POLH (0.51) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4168940 | 0.88 | ADORA3 (0.42) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4158975 | 0.88 | ABCB1 (0.48) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4157272 | 0.85 | ABCB1 (0.46) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4152427 | 0.84 | ALOX5 (0.46) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4161767 | 0.84 | ALOX5 (0.46) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4158702 | 0.84 | ALOX5 (0.46) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4158689 | 0.84 | ALOX5 (0.46) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4163511 | 0.84 | ALOX5 (0.46) | ABCB1ABCG2CYP3A4POLBKDM4E | |
| SCHEMBL4164389 | 0.84 | ALOX5 (0.46) | ABCB1ABCG2CYP3A4POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | ABCB1 1605/4885ABCG2 102/4885CYP3A4 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.