SCHEMBL4160023

SCHEMBL4160023

O=C(OC1CC=CC1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRNA7 P36544 5/20 0.57
▸ MEN1 O00255 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ GAA P10253 1/20 0.56
▸ HTR3E A5X5Y0 1/20 0.54
▸ HTR3B O95264 1/20 0.54
▸ HTR3A P46098 1/20 0.54
▸ HTR3D Q70Z44 1/20 0.54
▸ HTR3C Q8WXA8 1/20 0.54
▸ APOBEC3A P31941 1/20 0.53
▸ APOBEC3G Q9HC16 1/20 0.53
▸ F2 P00734 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ TSHR P16473 2/20 0.49
▸ SCN1A P35498 1/20 0.47
▸ SCN2A Q99250 1/20 0.47
▸ SCN3A Q9NY46 1/20 0.47
▸ CARM1 Q86X55 1/20 0.47
▸ PRMT6 Q96LA8 1/20 0.47
▸ POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8526842 0.88 CHRNA7 (0.54) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL4453290 0.83 MEN1 (0.69) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL1786140 0.83 MEN1 (0.69) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL31000129 0.81 CHRNA7 (0.63) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL9592504 0.80 POLB (0.49) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL9518832 0.80 POLB (0.49) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL9517909 0.80 POLB (0.49) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL9248196 0.80 MEN1 (0.65) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL1926317 0.80 MEN1 (0.65) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL21286806 0.79 MEN1 (0.59) CHRNA7MEN1KMT2AGAAHTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600728-B2 Interleukin-17 inhibitors NOVARTIS AG (CH) 2026-04-14 — — US disclosed
EP-4642785-A1 IL-17A MODULATORS Usynova Pharmaceuticals Ltd. (CN) 2025-11-05 — — EP disclosed
WO-2024138286-A1 IL-17A MODULATORS USYNOVA PHARMACEUTICALS, LTD. (CN) 2024-07-04 — — WO disclosed
WO-2024139171-A1 IL-17A MODULATORS USYNOVA PHARMACEUTICALS, LTD. (CN) 2024-07-04 — — WO disclosed
US-20230391782-A1 INTERLEUKIN-17 INHIBITORS NOVARTIS AG (CH) 2023-12-07 — — US disclosed
EP-4237417-A1 INTERLEUKIN-17 INHIBITORS Novartis AG (CH) 2023-09-06 — — EP disclosed
CN-116323596-A Interleukin-17 inhibitors 诺华股份有限公司 2023-06-23 — — CN disclosed
WO-2022091056-A1 INTERLEUKIN-17 INHIBITORS NOVARTIS AG (CH) 2022-05-05 — — WO disclosed
EP-3019196-B1 COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2018-06-06 — — EP disclosed
EP-3019196-B1 COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2018-06-06 — — EP disclosed
US-20110274648-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-11-10 — — US disclosed
US-20110274648-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-11-10 — — US disclosed
WO-2011060000-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2011-05-19 — — WO disclosed
WO-2011059887-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2011-05-19 — — WO disclosed
US-20090048203-A1 SUBSTITUTED ADENINES AND THE USES THEREOF ASTRAZENECA AB (SE) 2009-02-19 — — US disclosed
EP-1805196-A1 SUBSTITUTED ADENINES AND THE USE THEREOF AstraZeneca AB (SE) 2007-07-11 — — EP disclosed
WO-2006040558-A1 SUBSTITUTED ADENINES AND THE USE THEREOF ASTRAZENECA AB (SE) 2006-04-20 — — WO disclosed
US-6313365-B1 Ruthenium metathesis catalyst and method for producing olefin reaction product by metathesis reaction using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-11-06 — — US disclosed
US-6175047-B1 A CATALYST MIXTURE INCLUDING A RUTHENIUM COMPOUND, A DIHALOGENO COMPOUND, A TERMINAL ALKYNE; AS A CATALYST FOR A CARBON-CARBON BOND FORMATION REACTION TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-01-16 — — US disclosed
EP-0927577-A1 Ruthenium metathesis catalyst and method for producing olefin reaction product by metathesis reaction using the same Takasago International Corporation (JP) 1999-07-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391782-A1 INTERLEUKIN-17 INHIBITORS IL17A, IL2, IL18 CHRNA7 2551/4885MEN1 3778/4885KMT2A 3012/4885
US-20090048203-A1 SUBSTITUTED ADENINES AND THE USES THEREOF HPRT1, APRT, NUDT1 CHRNA7 4487/4885MEN1 2161/4885KMT2A 1961/4885
US-20110274648-A1 Hepatitis C Virus Inhibitors HAVCR2, PYGL, HCCS CHRNA7 4585/4885MEN1 4867/4885KMT2A 4516/4885
US-12600728-B2 Interleukin-17 inhibitors IL17A, IL2, IL1B CHRNA7 1638/4885MEN1 3383/4885KMT2A 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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