Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.80 |
| ▸ | DPP4 | P27487 | 1/20 | 0.80 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.80 |
| ▸ | RELA | Q04206 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | ATM | Q13315 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847648 | 1.00 | ABCG2 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| SCHEMBL30545313 | 0.90 | ABCG2 (0.82) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain C SCHEMBL144230 | 0.89 | NFKB1 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain A SCHEMBL2289181 | 0.89 | ABCG2 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain A SCHEMBL29349587 | 0.89 | ABCG2 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain C SCHEMBL25201341 | 0.89 | NFKB1 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain A SCHEMBL25209870 | 0.89 | ABCG2 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain A SCHEMBL2289188 | 0.89 | ABCG2 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain C SCHEMBL30384247 | 0.89 | NFKB1 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain C SCHEMBL144231 | 0.89 | NFKB1 (1.00) | ABCG2NFKB1DPP4NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149530-A1 | Antiinfective Flavonol Compounds and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2009-06-11 | — | — | US | disclosed |
| US-4605674-A | VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1986-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149530-A1 | Antiinfective Flavonol Compounds and Methods of Use Thereof | MPO, MIF, VIP | ABCG2 1910/4885NFKB1 523/4885DPP4 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.