Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419198 | 0.85 | TAS2R14 (0.35) | NOTUMTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL416168 | 0.81 | CFTR (0.41) | CFTRNOTUMPDK2PDK4CA12 | |
| SCHEMBL28974025 | 0.77 | CA12 (0.41) | CFTRPDK2PDK4CA12CA1 | |
| SCHEMBL420552 | 0.74 | — | — | |
| SCHEMBL18761745 | 0.74 | CA1 (0.39) | CFTRPDK2PDK4CA12CA1 | |
| SCHEMBL412257 | 0.74 | TAS2R14 (0.42) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8491481 | 0.74 | CFTR (0.43) | CFTRNOTUMPDK2PDK4CA12 | |
| SCHEMBL1235473 | 0.74 | CFTR (0.43) | CFTRNOTUMPDK2PDK4CA12 | |
| SCHEMBL1234811 | 0.72 | CFTR (0.42) | CFTRNOTUMPDK2PDK4CA12 | |
| SCHEMBL25269151 | 0.72 | CFTR (0.44) | CFTRNOTUMPDK2PDK4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8603947-B2 | (4-haloalkyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-12-10 | — | — | US | disclosed |
| US-8536097-B2 | 4-(4-haloalkyl-3-thiobenzoyl)pyrazoles and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-09-17 | — | — | US | disclosed |
| US-20120021903-A1 | 4-(4-HALOALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20120021904-A1 | (4-HALOALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021904-A1 | (4-HALOALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | CBR3, CBR1, CYP8B1 | CFTR 988/4885NOTUM 918/4885PDK2 1025/4885 |
| US-20120021903-A1 | 4-(4-HALOALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | CBR3, CYP4X1, PRDX4 | CFTR 958/4885NOTUM 1496/4885PDK2 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.