Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LIG1 | P18858 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | HAAO | P46952 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412257 | 0.89 | TAS2R14 (0.42) | TAS2R14PKMLIG1RXRARXRB | |
| SCHEMBL416274 | 0.85 | CFTR (0.38) | PKMLIG1NOTUMALDH1A1KDM4E | |
| SCHEMBL417766 | 0.78 | TAS2R14 (0.38) | TAS2R14RXRARXRBHAAONOTUM | |
| SCHEMBL17396421 | 0.75 | HAAO (0.40) | RXRBHAAOMCL1NOTUMALDH1A1 | |
| SCHEMBL17593679 | 0.73 | KDM4E (0.43) | PKMMCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL17395308 | 0.73 | GPR35 (0.40) | HAAOMCL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8726320 | 0.73 | ALDH1A1 (0.41) | MCL1NOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL976616 | 0.72 | NOTUM (0.39) | TAS2R14PKMLIG1RXRARXRB | |
| SCHEMBL1230305 | 0.72 | NOTUM (0.39) | TAS2R14PKMLIG1RXRARXRB | |
| SCHEMBL31440663 | 0.72 | NOTUM (0.39) | TAS2R14PKMLIG1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595955-B1 | (4-HALOGENALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER IP GMBH (DE) | 2016-11-30 | — | — | EP | disclosed |
| EP-2595963-B1 | 4-(4-HALOGENALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER IP GMBH (DE) | 2014-11-12 | — | — | EP | disclosed |
| US-8603947-B2 | (4-haloalkyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-12-10 | — | — | US | disclosed |
| US-8536097-B2 | 4-(4-haloalkyl-3-thiobenzoyl)pyrazoles and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-09-17 | — | — | US | disclosed |
| EP-2595963-A1 | 4-(4-HALOGENALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595955-A1 | (4-HALOGENALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20120021904-A1 | (4-HALOALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20120021903-A1 | 4-(4-HALOALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| WO-2012010575-A1 | (4-HALOGENALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010573-A1 | 4-(4-HALOGENALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021904-A1 | (4-HALOALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | CBR3, CBR1, CYP8B1 | TAS2R14 1504/4885PKM 2791/4885LIG1 2247/4885 |
| US-20120021903-A1 | 4-(4-HALOALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | CBR3, CYP4X1, PRDX4 | TAS2R14 954/4885PKM 1345/4885LIG1 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.