Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 4/20 | 0.72 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | BRD1 | O95696 | 1/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416330 | 0.87 | ACLY (0.62) | ACLYPTGDR2TSHRNPC1PGR | |
| SCHEMBL21999965 | 0.84 | ACLY (1.00) | ACLYPTGDR2 | |
| SCHEMBL13146531 | 0.80 | PGR (0.67) | ACLYPTGDR2PGRMEN1KMT2A | |
| SCHEMBL8668137 | 0.80 | TSHR (0.60) | ACLYPTGDR2TSHRNPC1MCL1 | |
| SCHEMBL13146584 | 0.77 | CCR2 (0.64) | ACLYTRIM24BRD1BRPF1PGR | |
| SCHEMBL3558901 | 0.77 | MAPK1 (0.57) | ACLYPTGDR2TSHRNPC1MCL1 | |
| SCHEMBL4695209 | 0.76 | PPARG (0.69) | ACLYPTGDR2 | |
| SCHEMBL4517372 | 0.76 | PTGDR2 (1.00) | ACLYPTGDR2 | |
| SCHEMBL31696798 | 0.75 | MAPK1 (0.70) | TSHRMCL1HPGDARPGR | |
| SCHEMBL7572911 | 0.74 | NPC1 (1.00) | TSHRNPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120064062-A1 | INHIBITORS OF BACTERIAL PLASMINOGEN ACTIVATORS | MICROBIOTIX, INC. | 2012-03-15 | — | — | US | disclosed |
| US-20120064062-A1 | INHIBITORS OF BACTERIAL PLASMINOGEN ACTIVATORS | MICROBIOTIX, INC. | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064062-A1 | INHIBITORS OF BACTERIAL PLASMINOGEN ACTIVATORS | PLG, PLAU, TFPI | ACLY 2156/4885PTGDR2 1317/4885TSHR 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.