Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ACLY | P53396 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666217 | 0.87 | KMT2A (0.51) | TSHRNPC1MCL1MEN1KMT2A | |
| SCHEMBL8665171 | 0.87 | ACLY (0.54) | TSHRNPC1MCL1MEN1KMT2A | |
| SCHEMBL8666204 | 0.83 | ALDH1A1 (0.54) | TSHRNPC1MCL1MEN1KMT2A | |
| SCHEMBL416295 | 0.80 | ACLY (0.72) | TSHRNPC1MCL1MEN1KMT2A | |
| SCHEMBL8668297 | 0.78 | WDR5 (0.48) | TSHRNPC1MEN1KMT2AACLY | |
| SCHEMBL7572911 | 0.75 | NPC1 (1.00) | TSHRNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL3558901 | 0.74 | MAPK1 (0.57) | TSHRNPC1MCL1MEN1KMT2A | |
| SCHEMBL2528312 | 0.73 | LMNA (0.67) | TSHRMCL1MEN1KMT2AMAPT | |
| SCHEMBL27508885 | 0.73 | KMT2A (0.53) | TSHRMEN1KMT2AHTTHPGD | |
| SCHEMBL8667441 | 0.72 | MCL1 (0.58) | TSHRMCL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0881220-A1 | DIARYLSULTAM DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-02 | — | — | EP | disclosed |