Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641949 | 0.85 | SLC9A1 (0.57) | ALDH1A1GSK3AGSK3BKDM4ERAB9A | |
| SCHEMBL8819921 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GSK3AGSK3BKDM4ERAB9A | |
| SCHEMBL4174300 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4ERAB9ACYP1A2CYP2C9 | |
| SCHEMBL7082273 | 0.73 | ALDH1A1 (0.49) | ALDH1A1GSK3AGSK3BKDM4ERAB9A | |
| SCHEMBL8819789 | 0.72 | ALDH1A1 (0.40) | ALDH1A1GSK3AGSK3BKDM4ERAB9A | |
| SCHEMBL28828879 | 0.71 | TSHR (0.50) | ALDH1A1KDM4ERAB9ACYP1A2CYP2C9 | |
| SCHEMBL7643580 | 0.71 | SLC9A1 (0.58) | ALDH1A1KDM4ERAB9ASLC9A1 | |
| SCHEMBL10048132 | 0.70 | GABRA1 (0.47) | ALDH1A1GSK3AGSK3BKDM4ERAB9A | |
| SCHEMBL12709665 | 0.69 | ALDH1A1 (0.60) | ALDH1A1GSK3AGSK3BKDM4ERAB9A | |
| SCHEMBL9089847 | 0.69 | ALDH1A1 (0.50) | ALDH1A1GSK3AGSK3BKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149485-A1 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2009-06-11 | — | — | US | disclosed |
| WO-2007122634-A2 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149485-A1 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | TK1, LCK, FYN | ALDH1A1 1813/4885GSK3A 195/4885GSK3B 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.