Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.61 |
| ▸ | CDK4 | P11802 | 1/20 | 0.60 |
| ▸ | CCND1 | P24385 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | AANAT | Q16613 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13962631 | 0.87 | PTGS2 (0.60) | KMT2APTGS2MEN1CDK4CCND1 | |
| SCHEMBL14520190 | 0.87 | KMT2A (0.61) | KMT2APTGS2MEN1LMNACYP1A2 | |
| SCHEMBL11483618 | 0.83 | KMT2A (0.68) | KMT2AMEN1HSD17B2CDK4CCND1 | |
| SCHEMBL4302838 | 0.83 | SMN1; SMN2 (0.58) | KMT2APTGS2MEN1MAPTSMN1; SMN2 | |
| SCHEMBL9118459 | 0.81 | AANAT (0.71) | KMT2AMEN1HSD17B2MAPTAANAT | |
| SCHEMBL10069200 | 0.80 | AANAT (0.77) | KMT2AMEN1HSD17B2AANATLMNA | |
| SCHEMBL21255779 | 0.80 | KMT2A (0.69) | KMT2AMEN1MAPTLMNACYP1A2 | |
| SCHEMBL798104 | 0.80 | MTNR1A (0.72) | KMT2AMEN1CYP1A2BLMPOLB | |
| SCHEMBL9751554 | 0.79 | MEN1 (0.67) | KMT2AMEN1CDK4CCND1MAPT | |
| SCHEMBL28654709 | 0.79 | PTGS2 (1.00) | KMT2APTGS2MEN1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010542-A1 | CYCLIC AMIDE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF | EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009010542-A1 | CYCLIC AMIDE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF | EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) | 2009-01-22 | — | — | WO | disclosed |