Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AANAT | Q16613 | 1/20 | 0.71 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069200 | 0.90 | AANAT (0.77) | AANATHSD17B2MEN1KMT2ANPC1 | |
| SCHEMBL22610207 | 0.90 | HSD17B2 (0.65) | AANATHSD17B2MEN1KMT2ANPC1 | |
| SCHEMBL27334858 | 0.89 | ALDH1A1 (0.76) | AANATHSD17B2MEN1KMT2ANPC1 | |
| SCHEMBL9117842 | 0.88 | MEN1 (0.76) | AANATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7852879 | 0.85 | GFER (0.84) | AANATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7677886 | 0.85 | MEN1 (0.84) | AANATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5903804 | 0.85 | AANAT (0.77) | AANATHSD17B2MEN1KMT2ANPC1 | |
| SCHEMBL6394942 | 0.84 | MEN1 (0.76) | AANATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11483618 | 0.84 | KMT2A (0.68) | HSD17B2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL918966 | 0.84 | MEN1 (0.78) | AANATMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025514-A1 | COMPOUNDS USEFUL AS ANXIOLYTIC, SEDATIVE, AND HYPNOTIC AGENTS | DISCOVERY THERAPEUTICS, INC. (US) | 1995-09-28 | — | — | WO | claimed |
| US-9284270-B2 | Boronic acid catalysts and methods of use thereof for activation and transformation of carboxylic acids | THE GOVERNERS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-03-15 | — | — | US | disclosed |
| US-9284270-B2 | Boronic acid catalysts and methods of use thereof for activation and transformation of carboxylic acids | THE GOVERNERS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-03-15 | — | — | US | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| EP-2675816-A1 | BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS | The Governors of the University of Alberta (CA) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012109749-A1 | BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-08-23 | — | — | WO | disclosed |
| WO-1995025514-A1 | COMPOUNDS USEFUL AS ANXIOLYTIC, SEDATIVE, AND HYPNOTIC AGENTS | DISCOVERY THERAPEUTICS, INC. (US) | 1995-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | BCAT1, ME1, BCAT2 | AANAT 838/4885HSD17B2 847/4885MEN1 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.