Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725230 | 0.90 | ALOX5 (0.38) | MAPTALDH1A1HTTKDM4EGSTP1 | |
| SCHEMBL20592020 | 0.86 | MEN1 (0.32) | MAPTKMT2AHSD17B10 | |
| SCHEMBL17337902 | 0.80 | KMT2A (0.40) | MAPTALDH1A1HTTKDM4ECA1 | |
| SCHEMBL17373963 | 0.80 | VCAM1 (0.38) | MAPTALDH1A1HTTKDM4ECA1 | |
| SCHEMBL19402698 | 0.79 | VCAM1 (0.43) | MAPTALDH1A1HTTKDM4ECA1 | |
| SCHEMBL890351 | 0.79 | MAPT (0.37) | MAPTALDH1A1HTTKDM4ECA1 | |
| SCHEMBL2000685 | 0.79 | ALOX15 (0.41) | MAPTALDH1A1HTTKDM4ECA1 | |
| SCHEMBL20591996 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1KMT2A | |
| SCHEMBL31261009 | 0.77 | MAPT (0.36) | MAPTALDH1A1HTTKDM4ECA1 | |
| SCHEMBL23813739 | 0.77 | ALDH1A1 (0.37) | MAPTALDH1A1HTTKDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210255193-A1 | LYSINE REACTIVE PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2021-08-19 | — | — | US | disclosed |
| US-20210255193-A1 | LYSINE REACTIVE PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2021-08-19 | — | — | US | disclosed |
| EP-3642630-A1 | LYSINE REACTIVE PROBES AND USES THEREOF | The Scripps Research Institute (US) | 2020-04-29 | — | — | EP | disclosed |
| US-20180372751-A1 | LYSINE REACTIVE PROBES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-12-27 | — | — | US | disclosed |
| WO-2018237334-A1 | LYSINE REACTIVE PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-12-27 | — | — | WO | disclosed |
| US-20090047517-A1 | MULTILAYER POLYMER FILMS | THE UNIVERSITY OF MELBOURNE (AU) | 2009-02-19 | — | — | US | disclosed |
| US-20090047517-A1 | MULTILAYER POLYMER FILMS | THE UNIVERSITY OF MELBOURNE (AU) | 2009-02-19 | — | — | US | disclosed |
| US-20090047517-A1 | MULTILAYER POLYMER FILMS | THE UNIVERSITY OF MELBOURNE (AU) | 2009-02-19 | — | — | US | disclosed |