Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21465802 | 0.82 | OPRM1 (0.46) | ALOX15ALOX12KDM4EALDH1A1TP53 | |
| SCHEMBL18166890 | 0.79 | TRPA1 (0.54) | GABRA1GABRB2ALDH1A1TP53MAPK1 | |
| SCHEMBL8539519 | 0.77 | GABRA1 (0.50) | GABRA1GABRB2SLC6A2HTR2AHTR2B | |
| SCHEMBL647401 | 0.76 | OPRM1 (0.54) | GABRA1GABRB2ALOX15KDM4ECYP3A4 | |
| SCHEMBL6046238 | 0.76 | SLC7A5 (0.66) | ALOX15KDM4ERECQLHIF1AHSD17B10 | |
| SCHEMBL18091143 | 0.76 | CNR1 (0.50) | ALDH1A1HPGDMAPK1DRD2CNR1 | |
| Phosphoric Acid SCHEMBL28056683 | 0.75 | GABRA1 (0.46) | GABRA1GABRB2ESR1LMNACYP2C9 | |
| Phosphoric Acid SCHEMBL29099239 | 0.75 | GABRA1 (0.46) | GABRA1GABRB2ESR1LMNACYP2C9 | |
| SCHEMBL18091153 | 0.74 | CNR1 (0.48) | ALDH1A1HPGDMAPK1DRD2CNR1 | |
| SCHEMBL18091141 | 0.74 | CNR1 (0.48) | ALDH1A1HPGDMAPK1DRD2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090081134-A1 | Oral Care Compositions Comprising Tropolone Compounds and Essential Oils and Methods of Using The Same | PAN PAULINE | 2009-03-26 | — | — | US | disclosed |
| EP-1536759-A1 | ORAL CARE COMPOSITION COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS | Warner-Lambert Company LLC (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20040185010-A1 | Oral care compositions comprising tropolone compounds and essential oils and methods of using the same | MCNEIL-PPC, INC | 2004-09-23 | — | — | US | disclosed |
| WO-2004012692-A1 | ORAL CARE COMPOSITION COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-12 | — | — | WO | disclosed |
| US-20040018154-A1 | ORAL CARE COMPOSITIONS COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS AND METHODS OF USING THE SAME | MCNEIL-PPC, INC | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090081134-A1 | Oral Care Compositions Comprising Tropolone Compounds and Essential Oils and Methods of Using The Same | TMSB10, PIGS, TPM3 | GABRA1 2641/4885GABRB2 3843/4885ALOX15 21/4885 |
| US-20040185010-A1 | Oral care compositions comprising tropolone compounds and essential oils and methods of using the same | TMSB10, PIGS, TPM3 | GABRA1 2641/4885GABRB2 3843/4885ALOX15 21/4885 |
| US-20040018154-A1 | ORAL CARE COMPOSITIONS COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS AND METHODS OF USING THE SAME | TMSB10, PIGS, TPM3 | GABRA1 2641/4885GABRB2 3843/4885ALOX15 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.