Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793698 | 0.79 | KCNH2 (0.39) | HTTKCNH2 | |
| SCHEMBL4161023 | 0.79 | HRH3 (0.52) | MAPK1HTTHRH3KCNH2 | |
| SCHEMBL4237634 | 0.77 | SLC6A2 (0.50) | — | |
| SCHEMBL3724429 | 0.77 | SLC6A2 (0.50) | — | |
| SCHEMBL4160127 | 0.72 | MAPK1 (0.41) | MAPK1HTTHRH3KCNH2PTAFR | |
| SCHEMBL5226803 | 0.71 | SPHK1 (0.40) | KCNH2 | |
| SCHEMBL5193918 | 0.71 | HTR3A (0.40) | KCNH2 | |
| SCHEMBL1810499 | 0.70 | HRH3 (0.47) | MAPK1HTTHRH3KCNH2ADAM17 | |
| SCHEMBL4014376 | 0.70 | HRH3 (0.49) | MAPK1HTTHRH3KCNH2 | |
| SCHEMBL4764592 | 0.70 | HRH3 (0.54) | HRH3KCNH2PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074088-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008045371-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-04-17 | — | — | WO | claimed |