Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.33 |
| ▸ | CA2 | P00918 | 13/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776908 | 0.79 | HTR6 (0.42) | CA1CA2SMN1; SMN2 | |
| SCHEMBL385126 | 0.79 | LMNA (0.46) | LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL8849931 | 0.78 | HSD11B1 (0.43) | CA1CA2 | |
| SCHEMBL9694727 | 0.76 | CA1 (0.37) | CA1CA2LMNAMAPK1HTT | |
| SCHEMBL777838 | 0.73 | CA2 (0.44) | CA1CA2SMN1; SMN2 | |
| SCHEMBL9303979 | 0.72 | CA2 (0.50) | CA1CA2LMNA | |
| SCHEMBL9270354 | 0.71 | CA2 (0.45) | CA1CA2 | |
| SCHEMBL13893253 | 0.71 | CA1 (0.44) | CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL9457858 | 0.71 | CA2 (0.45) | CA1CA2 | |
| SCHEMBL3193439 | 0.70 | ALDH1A1 (0.56) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546113-A1 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | claimed |
| US-20090233962-A1 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1911751-A1 | AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| US-5312930-A | Useful in optical devices requiring second harmonic generation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0502955-A1 | FLUORINATED SULFONES/KETONES FOR NONLINEAR OPTICS. | DU PONT (US) | 1992-09-16 | — | — | EP | disclosed |
| WO-1991008198-A1 | FLUORINATED SULFONES/KETONES FOR NONLINEAR OPTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233962-A1 | Amide derivative and insecticide containing the same | CYP1A1, CYP4B1, CYP2E1 | CA1 2217/4885CA2 924/4885LMNA 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.