Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2122869 | 0.87 | METTL3 (0.38) | RHOCRHOAALDH1A1 | |
| SCHEMBL2616566 | 0.81 | HCRTR1 (0.52) | — | |
| SCHEMBL4167801 | 0.78 | DAGLA (0.38) | ALDH1A1DAGLAABHD6 | |
| SCHEMBL3496295 | 0.76 | TDP1 (0.35) | DAGLAABHD6 | |
| SCHEMBL2120243 | 0.74 | LTA4H (0.41) | — | |
| SCHEMBL2122874 | 0.73 | HCRTR1 (0.35) | ALDH1A1 | |
| SCHEMBL4167405 | 0.73 | ALDH1A1 (0.38) | ALDH1A1DAGLA | |
| SCHEMBL4153904 | 0.69 | MCHR1 (0.42) | OPRD1HRH3ALDH1A1DAGLAABHD6 | |
| SCHEMBL4157352 | 0.69 | MEN1 (0.40) | ALDH1A1DAGLAABHD6 | |
| SCHEMBL29479439 | 0.69 | CPT1A (0.39) | OPRD1HRH3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090022670-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022670-A1 | NOVEL COMPOUNDS | UGT1A1, UGT2B7, ABCB1 | RHOC 4569/4885RHOA 4399/4885OPRD1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.