Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20311540 | 0.79 | TDP1 (0.36) | TDP1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10385157 | 0.77 | MAPT (0.41) | TDP1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9505716 | 0.77 | MAPT (0.38) | TDP1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL218054 | 0.71 | TDP1 (0.67) | TDP1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1002997 | 0.71 | MAPT (0.59) | TDP1CYP1A2MAPTKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL28205022 | 0.69 | MAPT (0.58) | TDP1CYP1A2MAPTKDM4ENPC1 | |
| SCHEMBL219895 | 0.67 | TDP1 (0.61) | TDP1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12287691 | 0.67 | TDP1 (0.46) | TDP1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31486506 | 0.66 | MAPK14 (0.41) | TDP1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1537798 | 0.65 | ALDH1A1 (0.52) | TDP1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524885-B2 | Hydrazido derivatives of hyaluronic acid | PROCHON BIOTECH LTD. (IL) | 2013-09-03 | — | — | US | disclosed |
| EP-2492285-A1 | Hydrazido derivatives of hyaluronic acid | ProChon Biotech Ltd. (IL) | 2012-08-29 | — | — | EP | disclosed |
| US-20090149419-A1 | HYDRAZIDO DERIVATIVES OF HYALURONIC ACID | PROCHON BIOTECH LTD. (IL) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149419-A1 | HYDRAZIDO DERIVATIVES OF HYALURONIC ACID | CD44, HAAO, HPSE | TDP1 3412/4885LMNA 2618/4885CYP1A2 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.