SCHEMBL9505716

SCHEMBL9505716

NNc1ccc(NN)c(O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
TDP1 Q9NUW8 3/20 0.38
NPC1 O15118 2/20 0.38
POLB P06746 2/20 0.38
RAB9A P51151 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CA1 P00915 5/20 0.37
CA2 P00918 5/20 0.37
CA9 Q16790 4/20 0.37
CA12 O43570 2/20 0.37
CA6 P23280 2/20 0.37
CA5A P35218 2/20 0.37
CA7 P43166 2/20 0.37
CA5B Q9Y2D0 2/20 0.37
CA4 P22748 1/20 0.37
CA14 Q9ULX7 1/20 0.37
IDO1 P14902 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9036792 0.80 ARG1 (0.48) MAPTTDP1NPC1POLBRAB9A
SCHEMBL28347412 0.78 ALDH1A1 (0.47) CA1CA2CA9CA12CA7
SCHEMBL8793376 0.78 MAPT (0.52) MAPTNPC1POLBRAB9AKDM4E
SCHEMBL4167680 0.77 TDP1 (0.39) MAPTTDP1NPC1POLBRAB9A
SCHEMBL14465086 0.74 TSHR (0.52) MAPTNPC1RAB9AKDM4ELMNA
SCHEMBL8083862 0.74 CA6 (0.50) MAPTTDP1NPC1POLBRAB9A
SCHEMBL29291586 0.74 TRPA1 (0.52) MAPTTDP1NPC1RAB9AKDM4E
SCHEMBL29291588 0.74 ALDH1A1 (0.50) MAPTTDP1POLBKDM4ECA1
SCHEMBL29291587 0.74 CA9 (0.50) MAPTTDP1NPC1POLBKDM4E
SCHEMBL16761044 0.74 ALOX15 (0.44) KDM4ECA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5142690-A None JP disclosed
JP-H05142690-A DIRECT POSITIVE COLOR PHOTOGRAPHIC SENSITIVE MATERIAL AND IMAGE FORMING METHOD FUJI PHOTO FILM CO LTD 1993-06-11 JP disclosed