SCHEMBL4168924

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4168931	1.00	RELA (0.58)	RELANFE2L2APPTRPA1CYP19A1
	SCHEMBL4175333	0.90	TAAR1 (0.59)	RELANFE2L2CYP19A1TAAR1TUBB4A
	SCHEMBL4175338	0.90	TAAR1 (0.59)	RELANFE2L2CYP19A1TAAR1TUBB4A
	SCHEMBL4183390	0.82	CYP1A1 (0.54)	NFE2L2APPCYP19A1TAAR1CYP1A1
	SCHEMBL4183387	0.82	CYP1A1 (0.54)	NFE2L2APPCYP19A1TAAR1CYP1A1
	SCHEMBL4413617	0.81	TAAR1 (0.46)	RELANFE2L2CYP19A1TAAR1AHR
	SCHEMBL4169517	0.81	TAAR1 (0.46)	RELANFE2L2CYP19A1TAAR1AHR
	SCHEMBL4169512	0.81	TAAR1 (0.46)	RELANFE2L2CYP19A1TAAR1AHR
	SCHEMBL15099543	0.80	RELA (0.67)	RELANFE2L2APPTRPA1CYP19A1
	SCHEMBL8799920	0.80	NFE2L2 (0.58)	NFE2L2TRPA1CYP19A1CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.