Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 2/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1770809 | 0.70 | BDKRB2 (0.42) | BDKRB2 | |
| Hydrochloric Acid SCHEMBL3860801 | 0.68 | CA2 (0.38) | BDKRB2 | |
| Hydrochloric Acid SCHEMBL3860806 | 0.65 | BDKRB2 (0.32) | BDKRB2 | |
| SCHEMBL5779490 | 0.62 | AHR (0.39) | PTPRB | |
| Hydrochloric Acid SCHEMBL3862054 | 0.60 | CYSLTR1 (0.47) | BDKRB2 | |
| Hydrochloric Acid SCHEMBL4827329 | 0.59 | BDKRB2 (0.46) | BDKRB2 | |
| SCHEMBL18893282 | 0.58 | SLC6A3 (0.37) | — | |
| SCHEMBL3602183 | 0.58 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL12643289 | 0.56 | SLC6A3 (0.43) | PTPRB | |
| SCHEMBL974239 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186927-A1 | TRANS-9,10-DEHYDROEPOTHILONE C AND D, ANALOGS THEREOF AND METHODS OF MAKING THE SAME | KOSAN BIOSCIENCES, INC. (US) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186927-A1 | TRANS-9,10-DEHYDROEPOTHILONE C AND D, ANALOGS THEREOF AND METHODS OF MAKING THE SAME | TMSB10, TUBA1C, TUBB1 | BDKRB2 3323/4885PTPRB 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.