Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | CCR1 | P32246 | 3/20 | 0.73 |
| ▸ | CCR5 | P51681 | 3/20 | 0.73 |
| ▸ | CCR8 | P51685 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | MMP2 | P08253 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | GMNN | O75496 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | MMP9 | P14780 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | MMP8 | P22894 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthoquinoline SCHEMBL12541296 | 0.86 | LMNA (0.56) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL29367277 | 0.85 | CCR1 (1.00) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL8845760 | 0.85 | CCR1 (1.00) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL8312 | 0.85 | CCR1 (1.00) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL29354015 | 0.85 | CCR1 (1.00) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL27549979 | 0.83 | LMNA (0.84) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL5888469 | 0.83 | LMNA (0.84) | LMNACCR1CCR5CCR8KDM4E | |
| Benzoquinone SCHEMBL1512993 | 0.83 | LMNA (0.79) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL22982126 | 0.83 | CCR1 (0.94) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL21044608 | 0.83 | CCR1 (0.94) | LMNACCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714441-B2 | Mediator-stabilized reagent compositions for use in biosensor electrodes | ABBOTT DIABETES CARE INC. (US) | 2017-07-25 | — | — | US | claimed |
| US-20170059506-A1 | DIAGNOSTIC PRODUCTS HAVING AN ENZYME AND A STABILIZED COENZYME | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2017-03-02 | — | — | US | claimed |
| CN-102667474-B | Simplified magazining of integrated systems | 霍夫曼-拉罗奇有限公司 | 2017-02-08 | — | — | CN | claimed |
| US-9528977-B2 | Simplified storage of at least one test element including a dry reagent layer having an enzyme and a stabilized coenzyme | ROCHE DIABETES CARE, INC. (US) | 2016-12-27 | — | — | US | claimed |
| EP-2467717-B1 | Container with diagnostic test element | HOFFMANN LA ROCHE (CH) | 2014-12-31 | — | — | EP | claimed |
| US-20140216949-A1 | Mediator-Stabilized Reagent Compositions for Use in Biosensor Electrodes | ABBOTT DIABETES CARE INC. (US) | 2014-08-07 | — | — | US | claimed |
| US-8696884-B2 | Mediator stabilized reagent compositions for use in biosensor electrodes | ABBOTT DIABETES CARE INC. (US) | 2014-04-15 | — | — | US | claimed |
| US-20130001101-A1 | Biosensor Having Improved Hematocrit and Oxygen Biases | ABBOTT DIABETES CARE INC. | 2013-01-03 | — | — | US | claimed |
| US-20120325679-A1 | Mediator-Stabilized Reagent Compositions for Use in Biosensor Electrodes | ABBOTT DIABETES CARE INC. | 2012-12-27 | — | — | US | claimed |
| US-20120241335-A1 | SIMPLIFIED STORAGE OF INTEGRATED SYSTEMS | ROCHE DIABETES CARE, INC. | 2012-09-27 | — | — | US | claimed |
| US-20090095625-A1 | Mediator-Stabilized Reagent Compositions for Use in Biosensor Electrodes | ABBOTT DIABETES CARE INC. | 2009-04-16 | — | — | US | claimed |
| WO-2009049093-A1 | MEDIATOR-STABILIZED REAGENT COMPOSITIONS FOR USE IN BIOSENSOR ELECTRODES | ABBOTT DIABETES CARE INC. (US) | 2009-04-16 | — | — | WO | claimed |
| US-7504019-B2 | Biosensor electrode mediators for regeneration of cofactors | ABBOTT LABORATORIES (US) | 2009-03-17 | — | — | US | claimed |
| US-20070289881-A1 | BIOSENSOR ELECTRODE MEDIATORS FOR REGENERATION OF COFACTORS | ABBOTT LABORATORIES (US) | 2007-12-20 | — | — | US | claimed |
| EP-1801229-A1 | Biosensor electrode | Abbott Laboratories (US) | 2007-06-27 | — | — | EP | claimed |
| EP-1023455-B1 | BIOSENSOR ELECTRODE MEDIATORS FOR REGENERATION OF COFACTORS | ABBOTT LAB (US) | 2007-05-02 | — | — | EP | claimed |
| US-20040197935-A1 | Biosensor electrode mediators for regeneration of cofactors | ABBOTT DIABETES CARE INC. | 2004-10-07 | — | — | US | claimed |
| US-6736957-B1 | 1,10-PHENANTHROLINE QUINONE DERIVATIVE MEDIATORS; ACTIVE ELECTRODE COMPRISING NICOTINAMIDE CO- FACTOR-DEPENDENT ENZYME AND NICOTINAMIDE COFACTOR; DISPOSABLE, SINGLE-USE | ABBOTT LABORATORIES | 2004-05-18 | — | — | US | claimed |
| EP-1023455-A1 | BIOSENSOR ELECTRODE MEDIATORS FOR REGENERATION OF COFACTORS | Abbott Laboratories (US) | 2000-08-02 | — | — | EP | claimed |
| WO-1999019507-A1 | BIOSENSOR ELECTRODE MEDIATORS FOR REGENERATION OF COFACTORS | ABBOTT LABORATORIES (US) | 1999-04-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130001101-A1 | Biosensor Having Improved Hematocrit and Oxygen Biases | HBB, HBZ, HBG2 | LMNA 3922/4885CCR1 2637/4885CCR5 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.