Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PTGES | O14684 | 5/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156647 | 0.92 | ALDH1A1 (0.78) | ALDH1A1KDM4EDRD2GAAPTGES | |
| SCHEMBL10407060 | 0.88 | KDM4E (1.00) | ALDH1A1KDM4EDRD2GAAPTGES | |
| SCHEMBL11158740 | 0.79 | KDM4E (0.82) | ALDH1A1KDM4EDRD2PTGESALOX5 | |
| SCHEMBL11153382 | 0.79 | KDM4E (0.82) | ALDH1A1KDM4EDRD2PTGESALOX5 | |
| SCHEMBL11245260 | 0.79 | KDM4E (0.90) | ALDH1A1KDM4EDRD2PTGESALOX5 | |
| SCHEMBL11160288 | 0.79 | KDM4E (0.82) | ALDH1A1KDM4EDRD2PTGESALOX5 | |
| Lonazolac SCHEMBL25221 | 0.79 | KDM4E (1.00) | ALDH1A1KDM4EDRD2PTGESALOX5 | |
| SCHEMBL11159845 | 0.79 | KDM4E (0.82) | ALDH1A1KDM4EDRD2PTGESALOX5 | |
| Lonazolac SCHEMBL287156 | 0.78 | KDM4E (0.97) | ALDH1A1KDM4EDRD2PTGESALOX5 | |
| Lonazolac SCHEMBL1478078 | 0.78 | KDM4E (0.97) | ALDH1A1KDM4EDRD2PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252723-B2 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2012-08-28 | — | — | US | disclosed |
| US-20090036310-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic Acids, Processes for Their Preparation and Their Use as Herbicides and Plant Growth Regulators | BAYER CORPSCIENCE GMBH (DE) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036310-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic Acids, Processes for Their Preparation and Their Use as Herbicides and Plant Growth Regulators | DDT, DDC, HPD | ALDH1A1 396/4885KDM4E 224/4885DRD2 2496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.