Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170112 | 0.84 | KMT2A (0.53) | P2RY2TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29019844 | 0.79 | ASAH1 (0.48) | P2RY2KDM4EALDH1A1POLBMAPT | |
| SCHEMBL4157745 | 0.75 | ALDH1A1 (0.54) | P2RY2KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL4174362 | 0.73 | KDM4E (0.49) | P2RY2TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7830622 | 0.73 | PIK3R1 (0.44) | P2RY2KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL4167785 | 0.73 | KDM4E (0.48) | L3MBTL1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL4158442 | 0.70 | KDM4E (0.48) | L3MBTL1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL4179886 | 0.70 | TDP1 (0.43) | TDP1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL692624 | 0.68 | LMNA (0.61) | KDM4EKMT2A | |
| SCHEMBL456749 | 0.68 | HPGD (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149485-A1 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2009-06-11 | — | — | US | claimed |
| WO-2007122634-A2 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2007-11-01 | — | — | WO | claimed |
| US-20090149485-A1 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2009-06-11 | — | — | US | disclosed |
| WO-2007122634-A2 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149485-A1 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | TK1, LCK, FYN | P2RY2 530/4885TDP1 338/4885L3MBTL1 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.