Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.45 |
| ▸ | CDH1 | P12830 | 1/20 | 0.45 |
| ▸ | APC | P25054 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.45 |
| ▸ | ADH5 | P11766 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697449 | 0.80 | TRPV1 (0.51) | TSHRALOX15KDM4EMAP2K4CDH1 | |
| SCHEMBL3874091 | 0.79 | TRPV1 (0.56) | RXRARXRBKDM4EADH5MKNK1 | |
| SCHEMBL17908089 | 0.77 | NAPRT (0.49) | RXRARXRBTSHRALOX15KDM4E | |
| SCHEMBL2904162 | 0.77 | ABCC4 (0.50) | RXRARXRBTSHRKDM4EALDH1A1 | |
| SCHEMBL11145941 | 0.76 | KDM4E (0.48) | ALOX15KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3325880 | 0.76 | PDE3B (0.43) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2040773 | 0.74 | FFAR2 (0.47) | CA12CA9RXRAKDM4EALDH1A1 | |
| SCHEMBL29788291 | 0.74 | FFAR2 (0.47) | CA12CA9RXRAKDM4EALDH1A1 | |
| SCHEMBL31227325 | 0.74 | LMNA (0.44) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL22861594 | 0.73 | TP53 (0.60) | CA12CA9RXRARXRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199965-B2 | Benzoimidazole derivatives and pharmaceutical composition comprising the same | DAEWOONG CO., LTD. (KR) | 2015-12-01 | — | — | US | disclosed |
| EP-1861387-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | DAE WOONG PHARMA (KR) | 2014-04-16 | — | — | EP | disclosed |
| CN-101128452-B | Novel benzimidazole derivatives and pharmaceutical compositions containing the same | DAE WOONG PHARMA | 2012-11-21 | — | — | CN | disclosed |
| US-20090018124-A1 | Novel Benzoimidazole Derivatives and Pharmaceutical Composition Comprising the Same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2009-01-15 | — | — | US | disclosed |
| CN-101128452-A | Novel benzimidazole derivatives and pharmaceutical compositions containing the same | DAE WOONG PHARMA (KR) | 2008-02-20 | — | — | CN | disclosed |
| EP-1861387-A1 | NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006080821-A1 | NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018124-A1 | Novel Benzoimidazole Derivatives and Pharmaceutical Composition Comprising the Same | TRPV1, TRPA1, BDKRB2 | CA12 4401/4885CA9 4080/4885RXRA 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.