SCHEMBL4174575

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4169455	1.00	TPSAB1 (0.43)	TPSAB1TPSD1TPSG1NPC1TDP1
	SCHEMBL4169463	1.00	TPSAB1 (0.43)	TPSAB1TPSD1TPSG1NPC1TDP1
	SCHEMBL4178910	0.90	NPC1 (0.53)	NPC1TDP1POLBL3MBTL1GAA
	SCHEMBL4178908	0.90	NPC1 (0.53)	NPC1TDP1POLBL3MBTL1GAA
	SCHEMBL4178217	0.89	NPC1 (0.52)	NPC1TDP1POLBL3MBTL1MEN1
	SCHEMBL4178214	0.89	NPC1 (0.52)	NPC1TDP1POLBL3MBTL1MEN1
	SCHEMBL4175550	0.88	POLB (0.47)	TPSAB1TPSD1TPSG1NPC1TDP1
	SCHEMBL4175552	0.88	POLB (0.47)	TPSAB1TPSD1TPSG1NPC1TDP1
	SCHEMBL8800804	0.87	FKBP1A (0.56)	NPC1L3MBTL1MEN1KMT2AFKBP1A
	SCHEMBL8801535	0.82	L3MBTL1 (0.47)	POLBL3MBTL1GPR4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.