SCHEMBL4175552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4175550	1.00	POLB (0.47)	POLBL3MBTL1NPC1TDP1AR
	SCHEMBL4178910	0.91	NPC1 (0.53)	POLBL3MBTL1NPC1TDP1KMT2A
	SCHEMBL4178908	0.91	NPC1 (0.53)	POLBL3MBTL1NPC1TDP1KMT2A
	SCHEMBL4178214	0.90	NPC1 (0.52)	POLBL3MBTL1NPC1TDP1KMT2A
	SCHEMBL4178217	0.90	NPC1 (0.52)	POLBL3MBTL1NPC1TDP1KMT2A
	SCHEMBL4169463	0.88	TPSAB1 (0.43)	POLBL3MBTL1NPC1TDP1AR
	SCHEMBL4174575	0.88	TPSAB1 (0.43)	POLBL3MBTL1NPC1TDP1AR
	SCHEMBL4169455	0.88	TPSAB1 (0.43)	POLBL3MBTL1NPC1TDP1AR
	SCHEMBL8800804	0.88	FKBP1A (0.56)	L3MBTL1NPC1FKBP1AKMT2AMEN1
	SCHEMBL8801535	0.85	L3MBTL1 (0.47)	POLBL3MBTL1ARKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.