Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596962 | 0.92 | SMN1; SMN2 (0.73) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL3507819 | 0.92 | GAA (0.51) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL30531213 | 0.92 | SMN1; SMN2 (0.73) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL16616416 | 0.88 | GAA (0.51) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL16616207 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL28381224 | 0.86 | GAA (0.50) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL13754105 | 0.85 | KDM4E (0.51) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL13523984 | 0.83 | LMNA (0.50) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL3508267 | 0.83 | GAA (0.48) | SMN1; SMN2GAAKDM4EALOX15LMNA | |
| SCHEMBL20302447 | 0.81 | ACHE (0.49) | SMN1; SMN2GAAKDM4EALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170905-A | Synthetic method of sulfonamide compound | 台州学院 | 2020-05-19 | — | — | CN | claimed |
| CN-113173884-B | Method for synthesizing pyridine and derivative thereof by catalyzing hans ester 1, 4-dihydropyridine compound with titanocene dichloride | 陕西师范大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-111170905-B | Synthetic method of sulfonamide compound | 台州学院 | 2022-04-29 | — | — | CN | disclosed |
| CN-110105472-B | Z-N catalyst, preparation method and application thereof | 中国石油天然气股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-113173884-A | Method for synthesizing pyridine and derivatives thereof by catalyzing hans ester 1, 4-dihydropyridine compounds with titanocene dichloride | 陕西师范大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-107952483-B | Catalyst, reactor using the same, and method for preparing β -phenethyl alcohol | 万华化学集团股份有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-111170905-A | Synthetic method of sulfonamide compound | 台州学院 | 2020-05-19 | — | — | CN | disclosed |
| CN-107952483-A | A kind of catalyst, uses the reactor of the catalyst, and a kind of method for preparing bata-phenethyl alcohol | 万华化学集团股份有限公司 | 2018-04-24 | — | — | CN | disclosed |
| US-20090163535-A1 | Substituted Heteroarylalkanoic Acids | THE INSTITUES FOR PHARMACEUTICAL DISCOVERY, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| EP-1444228-B1 | SUBSTITUTED HETEROARYLALKANOIC ACIDS AND THEIR USE AS ALDOSE REDUCTASE INHIBITORS | INST FOR PHARM DISCOVERY INC (US) | 2008-05-21 | — | — | EP | disclosed |
| US-7361671-B2 | Substituted heteroarylalkanoic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, INC. (US) | 2008-04-22 | — | — | US | disclosed |
| US-20030166668-A1 | Substituted heteroarylalkanoic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, INC. A CORPORATION OF THE STATE OF DELAWARE | 2003-09-04 | — | — | US | disclosed |
| US-4209440-A | A PHENYLINDOLE AND A DIHYDROPYRIDINE DICARBOXYLATE | LABAZ (FR) | 1980-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163535-A1 | Substituted Heteroarylalkanoic Acids | GPR119, LIPA, LIPC | SMN1; SMN2 4596/4885GAA 317/4885KDM4E 4022/4885 |
| US-20030166668-A1 | Substituted heteroarylalkanoic acids | GPR119, LIPA, DDC | SMN1; SMN2 4572/4885GAA 319/4885KDM4E 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.